Quality of life in patients with hoarding disorder

Abstract

The aim of this study was to investigate health-related quality of life (QoL) in patients with hoarding disorder (HD). Fifty-four patients with a primary diagnosis of HD, and 24 age-and sexmatched healthy control (HC) participants, completed a battery of questionnaires including the Medical Outcomes Study 36-item Short-Form Health Survey (SF-36), Saving Inventory-Revised, and Depression, Anxiety, Stress Scales. Compared to HC participants, those with HD reported poorer health-related QoL across all domains of the SF-36. When controlling for comorbid affective symptoms, HD participants scored lower than did HC participants in the QoL domains of social functioning, emotional well-being, role limitations due to emotional problems, vitality, and general health. HD symptom severity predicted, beyond the effects of affective symptoms, lower QoL in social functioning, emotional well-being, role limitations due to emotional problems, vitality, and general health. Hoarding disorder (HD), a newly recognized diagnosis in the Diagnostic and Statistical Manual of Mental Disorders, 5 th Edition (DSM-5) (American Psychiatric Association, 2013), is defined as a persistent inability to discard possessions, often accompanied by excessive acquiring, resulting in severe clutter that precludes normal use of living spaces (Frost & Gross, 1993; Frost & Hartl, 1996). Though hoarding was initially conceptualized as a subtype of obsessive-compulsive disorder (OCD), and was initially studied in the context of OCD, a growing body of research points to distinctions between HD and OCD ✰ Funded by National Institute of Mental Health grant R01 MH101163. Clinicaltrials.gov identifier NCT01956344.

Correlates of obsessive-compulsive and related disorders symptom severity during the COVID-19 pandemic

“…For instance, OCD, the paradigmatic OCRD, has been described as the 6th leading psychiatric disorder in terms of Disability Adjusted Life Years (DALYs) ( Hollander et al, 2016 ). Different studies have now shown a decrease in several quality of life domains, as well as increased suicidality, in people with a range of OCRDs, including OCD ( Angelakis et al, 2015 ; Coluccia et al, 2016 ), BDD ( Angelakis et al, 2016 ; IsHak et al, 2012 ), and HD ( Chakraborty et al, 2012 ; Tolin et al, 2019 ). More recently, evidence has also emerged linking OCD ( Isomura et al, 2018 ) and HD ( Darke and Duflou, 2017 ; Tolin et al, 2008 ) to an increased risk of metabolic and cardiovascular complications, which further increase morbidity and early mortality ( Meier et al, 2016 ).…”

A critical review of cognitive behavioural therapy for hoarding disorder: How can we improve outcomes?

“…Although most individuals with HD also experience urges to acquire (Frost et al, 2009), excessive acquiring is a specifier rather than a required criterion for an HD diagnosis (American Psychiatric Association, 2013). HD affects approximately 2.5% of the population (Postlethwaite et al, 2019) and is associated with multiple safety hazards in the home (i.e., risk of fire, collapsing piles of objects and blocked exits; Frost et al, 2000), economic costs, social problems, work impairment and unemployment, and a poor quality of life (Mathes et al, 2019; Neave et al, 2017; Tolin et al, 2008; Tolin, Das, et al, 2019). Although cognitive behavioural therapy (CBT) is the standard treatment for HD, one third of individuals may prematurely drop out of treatment and less than one third of treatment completers may achieve clinically significant reductions in symptoms (Chandler et al, 2019; Frost et al, 2012; Gilliam et al, 2011; Mathews et al, 2018; Moulding et al, 2017; Muroff et al, 2012; O'Connor et al, 2018).…”

Electrophysiological dynamics of visuocortical processing in hoarding disorder

“…In addition to the core feature of difficulty discarding, individuals with hoarding disorder also frequently report other psychiatric symptoms such as anxiety and depression. Neurocognitive complaints are also common, including reported problems with organization, attention, and categorization (Davidson et al., 2019; Tolin et al., 2019). However, the neurobiological mechanisms underlying hoarding disorder are not yet well understood.…”