Quality of life in patients with multiple sclerosis in Serbia

Abstract

Our findings suggest that both disability and depression significantly influence the HRQoL in Serbian MS patients, with depressive symptoms having the major influence.

A novel approach to estimate the minimally important difference for the fatigue impact scale in multiple sclerosis patients

“…The high degree of average impairment in HRQOL reflected in the SF-36 scores was consistent with the observation that roughly 50% of the sample had an EDSS score of 6 or higher. Furthermore, in our sample, patterns of compromised SF-36 scores in HRQOL domains and increasing neurologic disability appeared consistent with previous findings [49,57,58].…”

Quality of Life in Patients With Multiple Sclerosis in Turkey: Relationship to Depression and Fatigue

“…Previous correlative studies have demonstrated relationships between various clinical parameters and diminished QOL in MS (Lobentanz et al, 2004;Newland, 2006). Most studies in subjects with MS have shown that depression and fatigue are two of the most common symptoms and are clearly associated with reduced QOL scores (Drulovic et al, 2007;Janardhan & Bakshi, 2002;Newland, 2006;Pollmann, Busch, & Voltz, 2005;Pittion-Vouyovitch et al, 2006). Fatigue is often considered a state of exhaustion distinct from depressed mood or physical weakness (Krupp, 2003).…”

Importance of an individual's evaluation of functional status for health-related quality of life in patients with multiple sclerosis

“…47,48 The outcomes of other studies suggest that patients with MS, and possibly those with other chronic diseases, are less concerned than their clinicians about physical disability in their illness, especially with regard to its impacts on HRQoL. 19,20,47 …”

“…In clinical practice, strategies aimed at improving patients suffering from MS are most frequently focused on patients with more severe disability. 20 In many cases health professionals perceive physical impairment as a relevant indicator of patients' poorer HRQoL, but in doing so, these professionals might overlook aspects of patients' own perception of their health status. That is, MS patients themselves may perceive physical functioning differently.…”