Quality of Life in Psychosis: Prevalence and Associated Factors in a Nigerian Clinical Population

Abstract

Aim of the study was to assess sociodemographic and clinical determinants of quality of life in psychotic patients in a general hospital population in Nigeria. Information was obtained on demography, duration of untreated illness (DUI) and functioning among Schizophrenia (368), schizoaffective disorder (70), and 214 patients with affective psychosis. Functioning was assessed using GAF, severity of psychopathology with PANSS and quality of life using WHOQoL-BREF. In general, the differences in the QoL across the three psychotic disorders were small. Linear regression analysis, showed that high GAF p < 0.001, medication adherence, p = 0.007 were associated with good QoL in schizophrenia, low PANSS p < 0.001 and short DUI p = 0.001 in schizoaffective disorder and low PANSS, high GAF p < 0.001 respectively in affective psychosis. QoL and its determinants in psychosis are not absolutely different. More research is required in this area.

Treatments for people living with schizophrenia in Sub‐Saharan Africa: an adapted realist review

“…). Similarly, in Nigeria, a large proportion of people with schizophrenia had not received treatment (Lasebikan & Owoaje ; Onofa et al. ).…”

Systematic review of global functioning and quality of life in people with psychotic disorders

“…Global functioning predicted QoL overall in most analyses (Alessandrini et al, 2016, Kusel et al, 2007, Lasebikan & Owoaje, 2015, Meijer et al, 2009, Norman et al, 2000, Rocca et al, 2016, Roe et al, 2011, Woon et al, 2010. Exceptions were Stubbs et al (2015) andPrince (2007).…”

“…Schizophrenia was the single diagnosis in 26 articles (62%), only four articles (Greenley et al, 1997, Holloway & Carson, 1999, Lasebikan & Owoaje, 2015, Stubbs et al, 2015 10%included participants with bipolar disorder or depressive disorder with psychotic symptoms.…”

The influence of adherence to antipsychotics medication on the quality of life among patients with schizophrenia in Indonesia

“…10 Some studies have found that medication side effects are one factor which could influence the quality of life for people with schizophrenia. 5,11,12 In addition, previous studies suggest that nonad-herence to antipsychotic medications may result in poor quality of life in patients with schizophrenia (Lasebikan & Owoaje, 2015). 13 Nonadherence to antipsychotic medications is a major factor that contributes to relapse and readmission.…”

“…5,11,12 In addition, previous studies suggest that nonad-herence to antipsychotic medications may result in poor quality of life in patients with schizophrenia (Lasebikan & Owoaje, 2015). 13 Nonadherence to antipsychotic medications is a major factor that contributes to relapse and readmission. 14,15 However, previous study suggests that many patients with schizophrenia are reported to experience dissatisfaction with mental health care providers and that a lack of access significantly predicted medication omission.…”