Quality of life in schizophrenia measured by the MOS SF‐36 and the Lancashire Quality of Life Profile: a comparison

Meijer, Carin J.; Schene, Aart H.; Koeter, Maarten W. J.

doi:10.1034/j.1600-0447.2002.1198.x

Cited by 41 publications

(57 citation statements)

References 42 publications

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“…The two assessment tools that we used, the SF-36 and the WHOQOL-BREF, have been reported to be sensitive instruments for measuring healthrelated QOL (HRQOL) in patients who are suffering from psychosis [5,23]. The SF-36 has also been recommended when comparison with normal individuals or other patient groups on HRQOL is relevant [23].…”

Section: Discussionmentioning

confidence: 99%

Impact of Untreated Psychosis on Quality of Life in Patients with First-episode Schizophrenia

et al. 2005

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Despite increasing interest in the quality of life (QOL) of psychiatric patients in recent years, few studies have focused on the potential adverse effects of the illness on QOL during the period of untreated psychosis. Our study compares the QOL of patients with first-episode schizophrenia when they first presented to the psychiatric service with that of the normal population, and identifies possible relationships with various clinical parameters. One hundred and seventeen patients with schizophrenia (aged 14-28 years) who entered the Early Assessment Services for Young People with Psychosis (EASY) programme in Hong Kong from June 2001 to January 2004 were assessed with the MOS 36 item Short Form Health Survey (SF-36) and the World Health Organization Quality of Life Measure, abbreviated Hong Kong version (WHOQOL-BREF(HK)). We compared their SF-36 scores with controls from the normal population matched by age, sex, marital status and educational level. We assessed clinical parameters including positive, negative and depressive symptoms by the Positive and Negative Syndrome Scale (PANSS), the Scale for Assessment of Negative Symptoms (SANS), and the Montgomery and Asberg Depression Rating Scale (MADRS). When compared with matched controls from the normal population, significantly lower scores in all of the eight scales of the SF-36 were found in our patient group (p < 0.005). Various QOL domain scores had significant inverse correlations with the total MADRS score. However, there was no significant correlation with other clinical parameters. Young patients with first-episode schizophrenia have poorer QOL in the period of untreated psychosis than their counterparts in the community. Amongst various clinical parameters, the severity of depressive symptoms correlates most with QOL.

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Section: Discussionmentioning

confidence: 99%

Impact of Untreated Psychosis on Quality of Life in Patients with First-episode Schizophrenia

et al. 2005

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“…positive/negative self-esteem, positive/negative affect and the general well-being score, from the LQoLP) [51] . Secondary factor analysis is used to search for underlying dimensions that may explain the correlations between the subscales of an instrument or instruments [55] .…”

Section: Discussionmentioning

confidence: 99%

Schizophrenia Psychopathology in a Kuwaiti Arab Sample

Zahid

Ohaeri²

2010

Psychopathology

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Background: The heterogeneity of schizophrenia psychopathology has led to a search for symptom clusters that could be related to broad features of the disease. The objectives of the study were to: (1) highlight the pattern of symptoms among Kuwaiti subjects with schizophrenia, using the ICD-10 symptom checklist; (2) assess the factor structure of the Brief Psychiatric Rating Scale 18 (BPRS-18) and BPRS-24, and (3) evaluate the relationship of the resulting factors with sociodemographic characteristics, age at onset of illness, family history of mental illness, objective indicators of quality of life, self-esteem, affect balance, family caregiver burden, patient’s perceptions of service satisfaction and needs for care. Method: Consecutive outpatients in stable condition were assessed with the BPRS and ICD-10 symptom checklist, as well as measures of quality of life, needs for care, service satisfaction and family caregiver burden. Results: There were 130 patients (66.1% men, mean age = 36.8 years, age at onset of illness = 24.2 years, duration of illness = 12.9 years). Of the ICD-10 symptoms, the commonest positive symptoms were hallucinations (58.5%) and delusions (72%). Catatonic symptoms were rare (2.9%). About a quarter of the subjects experienced 4 of the negative symptoms. In exploratory factor analysis, we broadly replicated the known syndromes for BPRS-24 (disorganization, positive, activation, manic, negative and depression) and BPRS-18 (negative, positive, activation and affect). In regression analyses, the variables independently associated with psychopathology were family income, negative affect, self-esteem, duration of illness, age, lack of money for enjoyment, met needs for care and caregiver tension. The negative syndrome had more significant associations with the variables investigated than the positive syndrome. Psychopathological scores were separable from indices of psychological well-being. Conclusion: In this first study of schizophrenia psychopathology from the Arab world, the clinical manifestations were similar to the data from the developed countries. The persistence of psychotic symptoms despite freely available antipsychotic treatment and the impact on caregiver burden call for attention to the perennial issue of treatment resistance and underscore the need for continued interaction with family members after the acute inpatient phase of treatment, in order to address the impact of symptoms.

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“…Admittedly, there are several statistical analyses that refer solely to the classification system of the SF-36, from which the classification system of the SF-6D is constructed [37][38][39][40][41][42][43][44][45][46][47][48][49][50][51][52][53][54]. There are, however, only a few studies in which the relations between the SF-36 and one or more different instruments have been investigated [55][56][57][58], and in only one of these analyses is a further generic instrument for measuring HRQoL considered [55]. Moreover, none of these studies actually refers to the SF-6D attributes that are applied for determining an index of HRQoL.…”

Section: Introductionmentioning

confidence: 99%

The classification systems of the EQ-5D, the HUI II and the SF-6D: what do they have in common?

2009

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Quality of life in schizophrenia measured by the MOS SF‐36 and the Lancashire Quality of Life Profile: a comparison

Cited by 41 publications

References 42 publications

Impact of Untreated Psychosis on Quality of Life in Patients with First-episode Schizophrenia

Impact of Untreated Psychosis on Quality of Life in Patients with First-episode Schizophrenia

Schizophrenia Psychopathology in a Kuwaiti Arab Sample

The classification systems of the EQ-5D, the HUI II and the SF-6D: what do they have in common?

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