Quality of life in thyroid eye disease: impact of quality of care

Estcourt, Stephanie; Quinn, Anthony G.; Vaidya, Bijay

doi:10.1530/eje-11-0055

Cited by 110 publications

(39 citation statements)

References 39 publications

(39 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…On the other hand, we believe that the present work is important because it suggests that RTX may be able to modify the natural course of the GO, even as a first-line treatment. An additional strength of this trial is the analysis of the impact of immunosuppression on the residual signs of disease and on the patients' QOL (28,29), which has rarely been reported in GO in a prospective design (30).…”

Section: Discussionmentioning

confidence: 99%

Efficacy of B-Cell Targeted Therapy With Rituximab in Patients With Active Moderate to Severe Graves' Orbitopathy: A Randomized Controlled Study

Salvi¹,

Vannucchi²,

Currò

et al. 2015

The Journal of Clinical Endocrinology & Metabolism

337

307

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Efficacy of B-Cell Targeted Therapy With Rituximab in Patients With Active Moderate to Severe Graves' Orbitopathy: A Randomized Controlled Study

Salvi¹,

Vannucchi²,

Currò

et al. 2015

The Journal of Clinical Endocrinology & Metabolism

337

307

View full text Add to dashboard Cite

show abstract

“…In fact, the HRQOL has been studied principally in the setting of orbitopathy [11,12], where it seems that a worsening HRQOL is related to the grade of ophthalmopathy [12]. However, no studies have so far focused on the impact of surgery on the subsequent HRQOL in GD patients.…”

Section: Introductionmentioning

confidence: 99%

Does thyroid surgery for Graves’ disease improve health-related quality of life?

et al. 2012

View full text Add to dashboard Cite

Purpose Graves' disease can induce alterations of the psychosocial well-being that negatively influence the overall well-being of patients. Among the current treatments, surgery has limited indications, and its impact on the health-related quality of life has not been well clarified. The aim of this study was to assess the impact of surgery on the quality of life. Methods Fifty-seven patients who underwent total thyroidectomy for Graves' disease in our surgical unit between April 2002 and December 2009 were administered a questionnaire concerning four issues: organic alterations and clinical manifestations, neurovegetative system disturbances, impairment of daily activities, psychosocial problems. Patients were retrospectively questioned after thyroidectomy about the presence of these symptoms in both the pre and postoperative periods. Results There was a significant improvement after surgery in all four areas. Organic manifestations and psychosocial problems had higher average improvements, as did some aspects of the neurovegetative system and difficulties in undertaking daily activities. There were no reports of a worsening of symptoms. Conclusions Surgery resolved the hyperthyroidism in 100 % of cases, and was associated with a quality of life improvement of about 70 % in the patients. Surgery can therefore provide an immediate and effective resolution of Graves' disease, with benefits in health-related quality of life.

show abstract

“…Since benign thyroid diseases are very common and the outcome of therapy cannot be exclusively based on laboratory findings, we need a comprehensive instrument to assess the health-related QoL [1]. Nowadays, the impairment of thyroid dysfunction or thyroid eye disease on QoL is well established [2][3][4][5][6][7]. However, the negative influence of other thyroid disorders such as benign goitre or chronic autoimmune thyroiditis on patients' QoL has been suggested in recent studies [8][9][10][11].…”

Section: Quality Of Life In Patients With Benign Thyroid Disordersmentioning

confidence: 99%

ThyPROpl — polska wersja kwestionariusza oceny jakości życia u pacjentów z chorobami tarczycy

Sawicka‐Gutaj

Watt

Sowiński

et al. 2015

Endokrynologia Polska

View full text Add to dashboard Cite

Introduction: Thyroid disorders have a significant impact on patients' quality of life. ThyPRO is a thyroid-specific quality of life (QoL) questionnaire applicable to patients with benign thyroid disorders. There is substantial evidence for its clinical validity and reliability in patients with benign thyroid disorders. Our aim was to develop a validated Polish version of this questionnaire (ThyPROpl). Material and methods: ThyPROpl was translated and validated according to standard methodology for translation of patient-reported outcomes (PRO). Firstly, two independent translations from English to Polish were performed by two translators native in Polish, and a consensus version was reached in collaboration with an in-country consultant. A third translator prepared a back-translation from Polish to English, which likewise was reviewed by the in-country consultant. The backwards translation was reviewed by a PRO translation expert native in English (Health Research Associates HRA) and by the developer of ThyPRO, who provided additional revisions. Finally, ThyPROpl was tested among five patients with thyroid disorders with cognitive interview techniques, and new changes and clarifications needed for its full understanding were made.

show abstract

Quality of life in thyroid eye disease: impact of quality of care

Cited by 110 publications

References 39 publications

Efficacy of B-Cell Targeted Therapy With Rituximab in Patients With Active Moderate to Severe Graves' Orbitopathy: A Randomized Controlled Study

Efficacy of B-Cell Targeted Therapy With Rituximab in Patients With Active Moderate to Severe Graves' Orbitopathy: A Randomized Controlled Study

Does thyroid surgery for Graves’ disease improve health-related quality of life?

ThyPROpl — polska wersja kwestionariusza oceny jakości życia u pacjentów z chorobami tarczycy

Contact Info

Product

Resources

About