Quality of Life Measures in the Miami HIV-1 Infected Drug Abusers Cohort: Relationship to Gender and Disease Status

Shor‐Posner, Gail; Lecusay, Robert; Míguez‐Burbano, Maria José; Quesada, José A.; Rodriguez, Alan; Ruiz, Phillip; O'Mellan, Sandra; Campa, Adriana; Rincón, Hernán G.; Wilkie, Fran; Page, J. Bryan; Baum, Marianna K.

doi:10.1016/s0899-3289(00)00035-3

Cited by 23 publications

(16 citation statements)

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“…Despite prior evidence that HIV-infected depressed women are significantly less likely to be adherent to HAART than their non-depressed counterparts (Cook et al 2002) and evidence of differential rates of depression as a function of gender among participants, this factor was secondary to alcohol and medication side effects as a predictor of adherence in the present study. These findings are also in contrast with prior evidence of poorer generalized quality of life (e.g., Shor-Posner et al 2000) and its impact on chronic, life-affirming behaviors such as adherence to prescription medication regimens.…”

Section: Discussioncontrasting

confidence: 99%

“…Research indicates a positive correlation between QOL and adherence to HAART (e.g., Carrieri et al 2003). Moreover, lower levels of QOL are reported in women than in men (Shor-Posner et al 2000), regardless of HIV status, which may reflect the inverse relationship between QOL and depression. Therefore, differential rates in adherence between men and women may be related to QOL.…”

Section: Introductionmentioning

confidence: 99%

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Gender and Other Psychosocial Factors as Predictors of Adherence to Highly Active Antiretroviral Therapy (HAART) in Adults with Comorbid HIV/AIDS, Psychiatric and Substance-related Disorder

et al. 2008

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This study assessed adherence to HAART among 67 HIV-infected adults, and the degree to which gender and psychological factors-including depression, drug and alcohol use, quality of life, and medication side effects-influenced adherence. Although overall adherence was greater than rates reported in similar studies, no significant difference in adherence was observed between men and women in the present sample. Medication side effects were a significant predictor of non-adherence in the sample at large and among women in particular, while alcohol dependence was a significant predictor of non-adherence only in women. Possible explanations are explored.

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Section: Discussioncontrasting

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Gender and Other Psychosocial Factors as Predictors of Adherence to Highly Active Antiretroviral Therapy (HAART) in Adults with Comorbid HIV/AIDS, Psychiatric and Substance-related Disorder

et al. 2008

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“…Since validated stroke-specific QOL scales were not available at the time of the design of this study, we used a validated generic QOL scale, the Spitzer QLI, 9 which has been used extensively in prior research in various diseases. [10][11][12] METHODS The Northern Manhattan Study (NOMAS) includes a population-based incident ischemic stroke follow-up study designed to determine predictors of stroke recurrence and prognosis in a multiethnic, urban population consisting of 63% Hispanic, 20% black, and 15% white residents. 13,14 Selection of NOMAS cohort.…”

mentioning

confidence: 99%

Quality of life declines after first ischemic stroke

Dhamoon

Moon²,

Paik³

et al. 2010

Neurology

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Objectives: Quality of life (QOL) after stroke is poorly characterized. We sought to determine long-term natural history and predictors of QOL among first ischemic stroke survivors without stroke recurrence or myocardial infarction (MI). Methods:In the population-based, multiethnic Northern Manhattan Study, QOL was prospectively assessed at 6 months and annually for 5 years using the Spitzer QOL index (QLI), a 10-point scale. Functional status was assessed using the Barthel Index (BI) at regular intervals, and cognition using the Mini-Mental State Examination at 1 year. Generalized estimating equations estimated the association between patient characteristics and repeated QOL measures over 5 years. Follow-up was censored at death, recurrent stroke, or MI.Results: There were 525 incident ischemic stroke patients Ն40 years (mean age 68.6 Ϯ 12.4 years). QLI declined after stroke (annual change Ϫ0.10, 95% confidence interval Ϫ0.17 to Ϫ0.04), after adjusting for age, sex, race-ethnicity, education, insurance, depressed mood, stroke severity, bladder continence, and stroke laterality. This decline remained when BI Ն95 was added to the model as a time-dependent covariate, and functional status also predicted QLI. Changes in QLI over time differed by insurance status (p for interaction ϭ 0.0017), with a decline for those with Medicaid/no insurance (p Ͻ 0.0001) but not Medicare/private insurance (p ϭ 0.98). Conclusions:In this population-based study, QOL declined annually up to 5 years after stroke among survivors free of recurrence or MI and independently of other risk factors. QLI declined more among Medicaid patients and was associated with age, mood, stroke severity, urinary incontinence, functional status, cognition, and stroke laterality. Neurology ® 2010;75:328 -334 GLOSSARY BI ϭ Barthel Index; CAD ϭ coronary artery disease; CHF ϭ congestive heart failure; CI ϭ confidence interval; CUMC ϭ Columbia University Medical Center; DM ϭ diabetes mellitus; GEE ϭ generalized estimating equation; HTN ϭ hypertension; MI ϭ myocardial infarction; MMSE ϭ Mini-Mental State Examination; NIHSS ϭ NIH Stroke Scale; NOMAS ϭ Northern Manhattan Study; QOL ϭ quality of life; QLI ϭ quality of life index.Stroke causes a significant decrease in quality of life (QOL), even among those who have no poststroke disability.1 Prior studies examining QOL in stroke survivors have been limited by hospitalized samples, 2 cross-sectional design, 3 small sample sizes, 2 and samples with both hemorrhagic and ischemic strokes. 1,2,4,5 Longitudinal studies have been limited by short follow-up and enrollment of patients in different stages of early poststroke recovery. Few long-term population-based studies have systematically examined QOL after stroke. Those studies have been limited by few follow-up assessments 5,6 and significant loss to follow-up. 5 No study, to our knowledge, has censored recurrent vascular events, and the natural history and determinants of long-term QOL after a single ischemic stroke are not known. Finally, the effect of acce...

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“…Ainsi, le contexte social, politique et économique qui caractérise la vie des femmes rend certaines d'entre elles plus vulnérables face au VIH/sida. Différentes études ont pu mettre en évidence une qualité de vie dégradée chez les femmes infectées par le VIH [4][5][6][7][8][9][10][11] ainsi que des difficultés particulières quant au ressenti des effets indésirables des thérapies antirétrovirales [12]. Afin d'appréhender au mieux cette notion abstraite de santé mentale [13], nous allons nous arrêter sur deux critères qui nous paraissent pertinents dans ce contexte : les tentatives de suicide [14,15] et la qualité de vie.…”

Section: Mots Clés : Q U a L I T é D E V I E S U I C I D E L I P unclassified

“…Marie PRÉAU 1 ' 2 -3 Anne-Déborah BOUHNIK 2 ' 3 Isabelle HEARD 45 , Cécile BRUNET-FRANÇOIS 6 , Vincent LEMOING 7 …”

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La santé mentale des femmes séropositives en France à l'ère des thérapies antirétrovirales : quelles différences avec les hommes ? Quels enjeux ?

et al. 2008

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Résumé C e t r a v a i l a p o u r o b j e c t i f d e p r é s e n t e r d i f f é r e n t s i n d i c a t e u r s r e l a t i f s à l a s a n t é m e n t a l e d e s f e m m e s i n f e c t é e s p a r l e V I H s u i v i e s e n F r a n c e . D a n s u n p r e m i e r t e m p s , n o u s u t i l i s e r o n s l e s d o n n é e s d e l ' e n q u ê t e V e s p a , a f i n d e p r é s e n t e r u n e a n a l y s e d e s f a c t e u r s a s s o c i é s a u x t e n t a t i v e s d e s u ic i d e . D a n s u n s e c o n d t e m p s , n o u s p r é s e n t o n s d e s r é s u l t a t s o b t e n u s à p a r t i r d e s d o n n é e s d e l a c o h o r t e A p r o c o d e p a t i e n t s i n f e c t é s p a r l e V I H e t s o u s t h é r a p i e s a n t i r é t r o v i r a l e s . N o u s p r o p o s o n s u n e a n a l y s e d e s f a ct e u r s a s s o c i é s à u n e m e i l l e u r e q u a l i t é d e v i e p h y s i q u e e t m e n t a l e t r o i s a n n é e s a p r è s l a m i s e s o u s t r a i t e m e n t . L e s d i f f é r e n t s r é s u l t a t s m e t t e n t e n é v i d e n c e u n i m p a c t i m p o r t a n t d e s s y m p t ô m e s l i p o d y s t r o p h i q u e s , a i n s i q u e d e s c a r a c t é r i s t i q u e s s o c i od é m o g r a p h i q u e s e t p s y c h o s o c i a l e s t e l l e s q u e l e s c o m p o r t e m e n t s d e d i s -c r i m i n a t i o n q u a n t à l a s a n t é m e n t a l e d e s f e m m e s i n f e c t é e s p a r l e V I H . L ' e n s e m b l e d e c e s r é s u l t a t s e s t d i s c u t é a u r e g a r d d e l ' é v o l u t i o n d e l a p r i s e e n c h a r g e d e s f e m m e s i n f e c t é e s p a r l e V I H , d a n s u n e l o g i q u e d ' o p t i m i s a t i o n d e s p r a t i q u e s d e s d i v e r s a c t e u r s c o n c e r n é s p a r c e t t e p r i s e e n c h a r g e . Mots clés : q u a l i t é d e v i e , s u i c i d e , l i p o d y s t r o p h i e s , e f f e t s s e c o n d a i r e s , c o r p o r é i t é , s a n t é m e n t a l e , d i s c r i m i n a t i o n .Suite à l'avènement des thérapies antirétrovirales, les personnes infectées par le VIH sont, pour une grande majorité, contraintes de suivre un traitement continu sur le long, voire très long terme. 151Article disponible sur le site

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Quality of Life Measures in the Miami HIV-1 Infected Drug Abusers Cohort: Relationship to Gender and Disease Status

Cited by 23 publications

References 20 publications

Gender and Other Psychosocial Factors as Predictors of Adherence to Highly Active Antiretroviral Therapy (HAART) in Adults with Comorbid HIV/AIDS, Psychiatric and Substance-related Disorder

Gender and Other Psychosocial Factors as Predictors of Adherence to Highly Active Antiretroviral Therapy (HAART) in Adults with Comorbid HIV/AIDS, Psychiatric and Substance-related Disorder

Quality of life declines after first ischemic stroke

La santé mentale des femmes séropositives en France à l'ère des thérapies antirétrovirales : quelles différences avec les hommes ? Quels enjeux ?

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