Quality of life of patients with central serous chorioretinopathy – a major cause of vision threat among middle-aged individuals

Abstract

Introduction: The 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25) was designed to measure the vision-related quality of life (QoL). We aimed to assess the effect of disease duration, disease type (i.e., acute vs. chronic and unilateral vs. bilateral), and selected sociodemographic data on the QoL of patients with central serous chorioretinopathy (CSC). Material and methods: The study included 79 patients diagnosed with CSC. The QoL was assessed using the NEI VFQ-25. The statistical analysis was performed using IBM SPSS Statistics 24. Results: A significant positive correlation was found between deterioration in peripheral vision as assessed by the NEI VFQ-25 and duration of CSC (r =-0.22, p = 0.046). Compared with women, men obtained higher scores on the scales assessing general health, mental health, ocular pain and role limitations (p = 0.018, p = 0.027, p = 0.009 and p = 0.007, respectively). Patients with acute CSC reported higher levels of social functioning as compared with those with chronic CSC (p = 0.04). There were no differences in any of the scales between patients with unilateral and bilateral CSC. Elderly patients obtained lower scores on 9 of the 12 analyzed scales, as compared with younger patients (p < 0.05). Conclusions: Patients with CSC do not assess their QoL in negative terms, which may be related to the fact that the disease presents with transient symptoms. However, the QoL deteriorated with longer disease duration. Men with CSC have better vision-related QoL than women.

Imbalance in the Levels of Angiogenic Factors in Patients with Acute and Chronic Central Serous Chorioretinopathy

“…Choroidal vasculature plays a crucial role in retinal homeostasis and preservation of good vision and vision-related Quality of Life [ 27 ]. Importantly, the key pathophysiologic mechanism in CSC is associated with the presence of abnormally thick choroid, hyperpermeable, and dilated choroidal vessels with or without RPE abnormalities overlying the pachyvessels [ 7 ].…”

Altered plasma cytokine levels in acute and chronic central serous chorioretinopathy

“…Central serous chorioretinopathy (CSC) is the fourth most common retinopathy after age‐related macular degeneration (AMD), diabetic retinopathy and retinal vein occlusion (Wang et al 2008). Progression of CSC over time may lead to vision disorder and deteriorated quality of life (Karska‐Basta et al 2020). There are two types of CSC: acute and chronic, with a threshold of between 4 and 6 months adopted in most published reports to distinguish between both entities (Daruich et al 2015).…”

Central Serous Chorioretinopathy and Personality Characteristics: A Systematic Review of Scientific Evidence over the Last 10 Years (2010 to 2020)

“…A chronic visual disease highly compromises quality of life [ 20 , 21 ]; therefore, the identification of risk factors is crucial for early treatment and intervention. An important line of research about CSC is currently focused on differences between patients with an acute disorder and those who develop a chronic disorder [ 22 , 23 , 24 ].…”