Quality of life of patients after low anterior, intersphincteric, and abdominoperineal resection for rectal cancer—a matched-pair analysis

Konanz, J; Herrle, Florian; Weiß, Christel; Post, Stefan; Kienle, Peter

doi:10.1007/s00384-013-1683-z

Cited by 97 publications

(90 citation statements)

References 30 publications

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“…On the QLQ-CR29 instrument, patients with sphincter preservation had higher scores for symptoms of fecal incontinence, bowel movement frequency, and buttock pain and constipation, as reported by other groups [16, 17, 20, 29]. …”

Section: Discussionmentioning

confidence: 64%

Late assessment of quality of life in patients with rectal carcinoma: comparison between sphincter preservation and definitive colostomy

Silva

Aguiar

Pastore

et al. 2018

Int J Colorectal Dis

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PurposePatients with cancer of the lower and middle rectum who are candidates for curative surgery often have negative opinions on definitive colostomy. The purpose of this study is to compare the quality of life (QoL) of patients who undergo standard treatment for rectal cancer with sphincter preservation or definitive colostomy.MethodsA total of 125 patients with adenocarcinoma of the lower or middle rectum who underwent radical surgery with curative intent with a follow-up ≥ 1 year were recruited: 83 patients (group 1) were subjected to low anterior resection and low colorectal or coloanal anastomosis—thus preserving their sphincter—and 42 (group 2) were treated with abdominoperineal resection, followed by terminal definitive colostomy. QoL was assessed with the EORTC QLQ-C30 and QLQ-CR29 questionnaires.ResultsHealth and global quality of life were similar between groups; however, patients who underwent definitive colostomy had higher scores on the emotional (p value = 0.016) and cognitive function scales (p value = 0.017). Patients with sphincter preservation presented with more symptoms that were related to stool frequency (p value < 0.001), intestinal constipation (p value = 0.005), fecal incontinence (p value = 0.001), buttock pain (p value = 0.023), and nausea and vomiting (p value = 0.036), whereas patients with permanent colostomy had higher scores for dysuria (p value = 0.033).ConclusionAlthough global QoL scores did not differ between groups, patients who underwent definitive colostomy had significantly better functional and symptom scale scores, reflecting greater function with fewer symptoms.Electronic supplementary materialThe online version of this article (10.1007/s00384-018-3044-4) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 64%

Late assessment of quality of life in patients with rectal carcinoma: comparison between sphincter preservation and definitive colostomy

Silva

Aguiar

Pastore

et al. 2018

Int J Colorectal Dis

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“…The average life span of the Japanese could still be increasing. More recently, some researchers reported that there was no difference in global QOL following ISR or CAA versus APR [32][33][34][35] . Patients may not always obtain benefits from sphincter preservation for treatment of LRC near the anus, and we should recognize that global QOL is not worse after APR than ISR.…”

Section: Discussionmentioning

confidence: 99%

Long-term assessment of anorectal function after extensive resection of the internal anal sphincter for treatment of low-lying rectal cancer near the anus

Shiokawa

Funahashi

Kaneko

et al. 2017

J Anus Rectum Colon

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Abstract:Objectives: Intersphincteric resection (ISR) for low-lying rectal cancer (LRC) may induce major problems associated with anorectal function. In this study, we assessed the severity of ISR-induced impairment in anorectal function. Methods: In total, 45 patients followed up regularly !2 years after diverting ileostoma closure were eligible. The patients underwent ISR (n=35) or conventional coloanal anastomosis without resection of the internal anal sphincter (IAS) (n=10) for treatment of LRC from January 2000 to December 2011. We retrospectively compared anorectal function [stool frequency, urgency, Wexner incontinence scale (WIS) score, and patient satisfaction with bowel movement habits on a visual analog scale (VAS) score] for !2 years after stoma closure between the two groups. Results: The median follow-up period was 4.0 years (range, 2.0-6.5 years). Of the total, 17 (48.6%) patients who underwent ISR had poor anorectal function, including two with complete incontinence. Significant differences were found between the groups in the incidence of urgency (p=0.042), WIS score (p=0.024), and defecation disorder with a WIS score of !10 (p= 0.034) but not in stool frequency. Based on the VAS score, 45.7% of patients who underwent ISR were dissatisfied with their bowel movement habits (p=0.041). Conclusions: Extensive resection of the IAS has negative short-and long-term effects on anorectal function.

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“…1 However, as compared with abdominoperineal resection, ISR and LAR can prevent the need for permanent colostomy to a greater extent. With all the above-mentioned procedures, the occurrence of anastomotic strictures is a potential serious postoperative adverse event that typically requires repeated treatment.…”

mentioning

confidence: 99%

Efficacy and safety of endoscopic radial incision and cutting for benign severe anastomotic stricture after surgery for lower rectal cancer (with video)

Osera

Ikematsu

Odagaki

et al. 2015

Gastrointestinal Endoscopy

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Quality of life of patients after low anterior, intersphincteric, and abdominoperineal resection for rectal cancer—a matched-pair analysis

Cited by 97 publications

References 30 publications

Late assessment of quality of life in patients with rectal carcinoma: comparison between sphincter preservation and definitive colostomy

Late assessment of quality of life in patients with rectal carcinoma: comparison between sphincter preservation and definitive colostomy

Long-term assessment of anorectal function after extensive resection of the internal anal sphincter for treatment of low-lying rectal cancer near the anus

Efficacy and safety of endoscopic radial incision and cutting for benign severe anastomotic stricture after surgery for lower rectal cancer (with video)

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