Quality of life outcomes are equivalent after lobectomy in the elderly

Burfeind, William R.; Tong, Betty C.; O'Branski, Erin E.; Herndon, James E.; Toloza, Eric M.; D’Amico, Thomas A.; Harpole, Linda H.; Harpole, David H.

doi:10.1016/j.jtcvs.2008.02.093

Cited by 60 publications

(43 citation statements)

References 20 publications

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“…These results are in line with previous evidence showing that traditional objective risk factors (i.e. age, chronic obstructive lung disease, forced expiratory volume in 1 s (FEV1), diffusing capacity of the lung for carbon dioxide) are generally not associated with residual quality of life [4][5][6][7][8].…”

Section: Quality Of Life After Lung Resection Is Not Associated With supporting

confidence: 91%

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Quality of life after lung resection is not associated with functional objective measures

et al. 2013

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Section: Quality Of Life After Lung Resection Is Not Associated With supporting

confidence: 91%

“…No adequately powered studies exist that demonstrate protection by the vaccine against inhalational anthrax in humans. Despite this, widespread vaccination of military personnel was undertaken by allied forces during the recent Gulf Wars [5].…”

Section: Inhalational Anthrax In a Vaccinated Soldiermentioning

confidence: 99%

Quality of life after lung resection is not associated with functional objective measures

et al. 2013

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“…However, no significant difference in pulmonary function between after ALT and after VATS has been found [6,21]. In the present study, VC and FEV1 were higher in older (>68 years) patients than in young patients, perhaps because older patients tend to tolerate pain relatively better [22].…”

Section: Discussioncontrasting

confidence: 65%

Pulmonary function after pulmonary resection by posterior thoracotomy, anterior thoracotomy or video-assisted surgery

Endoh

Tanaka

Yajima

et al. 2010

European Journal of Cardio-Thoracic Surgery

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Objective: Predicted postoperative forced expiratory volume in 1 s (ppoFEV1) is estimated in lung cancer patients before pulmonary resection, as well as the clinical stage. This study aims to evaluate ppoFEV1 and ppo-vital capacity (ppoVC) on postoperative day 7 (POD7) and to compare the results following video-assisted thoracic surgery (VATS) and open thoracotomy procedures. Methods: Of the 155 patients who underwent pulmonary resection, 70 had VATS; 30 had muscle-sparing thoracotomy (anterior limiting thoracotomy (AL)); and 55 had postero-lateral thoracotomy (PL). VC and FEV1 were measured on POD7 and compared with the VC and FEV1 before surgery using analysis of covariance (ANCOVA). The ratio of the actual-and the ppoVC and FEV1 was evaluated to identify factors associated with variations in postoperative residual VC/FEV1. Results: There were significant differences by analysis of covariance (ANCOVA) in the VC/FEV1 among the three surgical approaches. In the VATS group, the VC ratio and the FEV1 ratio were 96.5% and 94.7%, respectively; they were significantly higher in the VATS group than in the thoracotomy group (AL: 90.4% and 90.1%, respectively; PL: 87.4% and 87.6%, respectively). Non-chronic obstructive pulmonary disease (COPD) and upper lobectomy were also associated with a low VC ratio and FEV1 ratio. Conclusion: Predicted postoperative pulmonary function might be overestimated in COPD patients or in those undergoing VATS or lower lobectomy. #

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“…Interestingly, in elderly patients and in those traditionally deemed at increased surgical risk, the post-operative physiological or mental status did not differ from those of lower risk counterparts [197,201,202]. These findings may have great importance during patient counselling before the operation.…”

Section: Residual Function and Qol After Radical Treatmentmentioning

confidence: 81%

ERS/ESTS clinical guidelines on fitness for radical therapy in lung cancer patients (surgery and chemo-radiotherapy)

Brunelli¹,

Charloux²,

Bolliger³

et al. 2009

Eur Respir J

772

550

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A collaboration of multidisciplinary experts on the functional evaluation of lung cancer patients has been facilitated by the European Respiratory Society (ERS) and the European Society of Thoracic Surgery (ESTS), in order to draw up recommendations and provide clinicians with clear, up-to-date guidelines on fitness for surgery and chemo-radiotherapy.The subject was divided into different topics, which were then assigned to at least two experts. The authors searched the literature according to their own strategies, with no central literature review being performed. The draft reports written by the experts on each topic were reviewed, discussed and voted on by the entire expert panel. The evidence supporting each recommendation was summarised, and graded as described by the Scottish Intercollegiate Guidelines Network Grading Review Group. Clinical practice guidelines were generated and finalised in a functional algorithm for risk stratification of the lung resection candidates, emphasising cardiological evaluation, forced expiratory volume in 1 s, systematic carbon monoxide lung diffusion capacity and exercise testing.Contrary to lung resection, for which the scientific evidences are more robust, we were unable to recommend any specific test, cut-off value, or algorithm before chemo-radiotherapy due to the lack of data. We recommend that lung cancer patients should be managed in specialised settings by multidisciplinary teams.

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Quality of life outcomes are equivalent after lobectomy in the elderly

Abstract: By using a validated quality of life assessment tool with measurements at baseline and serially after resection in a large patient population, this analysis quantifies the degree of impairment of quality of life after lobectomy and documents time to full recovery for both age groups.

Cited by 60 publications

References 20 publications

Quality of life after lung resection is not associated with functional objective measures

Quality of life after lung resection is not associated with functional objective measures

Pulmonary function after pulmonary resection by posterior thoracotomy, anterior thoracotomy or video-assisted surgery

ERS/ESTS clinical guidelines on fitness for radical therapy in lung cancer patients (surgery and chemo-radiotherapy)

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