Quality-of-Life Outcomes in Oncology

Siddiqui, Farzan; Kachnic, Lisa A.; Movsas, Benjamin

doi:10.1016/j.hoc.2006.01.003

Cited by 26 publications

(9 citation statements)

References 96 publications

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“…Due to its broad coverage of individual’s feelings, beliefs and perceptions, there is a lack of consensus on the exact definition of quality of life (Siddiqui, Kachnic, & Movsas, 2006; Soni & Cella, 2002). However, health-related quality of life (HR-QOL) is defined as a combination of health status, functional status and quality of life (Guyatt, Feeny, & Patrick, 1993).…”

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confidence: 99%

“…In addition, HR-QOL has been found to be a predictor of survival in patients with head and neck, lung or colorectal cancer (Efficace et al, 2006; Karvonen-Gutierrez et al, 2008; Maione et al, 2009). Therefore, identifying which factors specifically contribute to poorer HR-QOL in cancer patients and exploring possible ways to improve HR-QOL, have become very important therapeutic goals (Siddiqui, Kachnic, & Movsas, 2006; Soni & Cella, 2002). …”

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confidence: 99%

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Decreased Health-Related Quality of Life in Women With Breast Cancer Is Associated With Poor Sleep

Liu

Fiorentino

Rissling

et al. 2013

Behavioral Sleep Medicine

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This study examined the longitudinal relationship between health-related quality of life (HR-QOL) and subjective and objective sleep quality in 166 women with newly diagnosed stage I-III breast cancer who were scheduled to receive ≥4 cycles of adjuvant/neoadjuvant chemotherapy. HR-QOL was assessed with the Medical Outcomes Study-Short Form Physical Component Scale and Mental Component Scale scores. Subjective sleep was assessed with the Pittsburgh Sleep Quality Index (PSQI); objective sleep was measured with actigraphy. Data were collected before starting chemotherapy and during the last week of cycle 4 of chemotherapy. Patients reported poor HR-QOL and poor sleep quality before and during chemotherapy. Short sleep time and long naps were recorded at both time points. The Mental Component score was related to reports of poor sleep but not to recorded sleep, worse Physical Component scores were associated with reports of poor sleep and less recorded nap time, suggesting sleep plays an important role in cancer patients’ HR-QOL.

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confidence: 99%

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confidence: 99%

Decreased Health-Related Quality of Life in Women With Breast Cancer Is Associated With Poor Sleep

Liu

Fiorentino

Rissling

et al. 2013

Behavioral Sleep Medicine

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“…Indeed, the annual number of publications in the field of QOL and oncology has risen from a mere 32 articles in 1973 to nearly 1000 by 1990 and 5444 by 2004. 22 An end result of this literature is that there are now in excess of 20,000 PRO-based assessments available, and normative data now exist for a large number of assessments such as the Functional Assessment of Cancer Therapy (FACT), EORTC, and Medical Outcomes Survey–Short Form series of measures. 23 For example, by testing large numbers of patients and individuals, using a 10-point Linear Analogue Self-assessment (LASA) scale, we can now identify baseline differences in QOL.…”

Section: The Evolution Of Qol Assessment In Cancermentioning

confidence: 99%

Metrics to Assess Quality of Life After Management of Early-Stage Lung Cancer

Sloan¹

2011

The Cancer Journal

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Quality of life (QOL) is a key clinical outcome in patients with lung cancer because of the debilitating nature of the disease and its treatments. In recent years, advances have been made in the assessment of QOL via patient-reported outcomes. A brief history of the evolution of QOL measures in oncology clinical trials and practice is given with specific reference to early-stage lung cancer. The role that QOL can play as a prognostic factor, especially among lung cancer patients, is delineated. The most commonly seen symptoms among lung cancer patients are listed. This review is intended to provide the clinical researcher with a summary of the alternative measures that are both valid and reasonable to consider when assessing QOL in early-stage lung cancer patients. Suggestions for QOL assessment in both a research setting and clinical environment are considered. A review of the most popular QOL assessments in general application to lung cancer and disease-specific measures is provided. An algorithm for selecting appropriate QOL assessments for lung cancer clinical research is provided. The primary conclusion from this work is that scientifically sound investigations into the QOL of early-stage lung cancer patients are feasible and encouraged so that the care of these patients can be optimized.

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“…Most agree that HRQOL is a multidimensional construct. 1 Breast cancer is a malignant proliferation of epithelial cells lining the ducts or lobules of the breast. Breast cancer is one of the most common cancers in women worldwide, with an incidence of about 570,000 patients per year.…”

Section: Introductionmentioning

confidence: 99%

“…QOL ratings by physicians or other medical personnel have been found to differ significantly from patient reports. 1,5 QOL studies have allowed oncologists to understand better the impact of various forms of cancer therapy on the patient's well-being and functioning and have guided caretakers in making recommendations to improve the patient's overall QOL. Knowledge gained from a QOL study can be used to communicate accurately to future patients treatment-related morbidities or resultant limitations in the functional and emotional well-being that are likely to occur.…”

Section: Introductionmentioning

confidence: 99%