1975
DOI: 10.1093/bja/47.1.41
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Quality of Spinal Extradural Anaesthesia: The Influence of Spinal Nerve Root Diameter

Abstract: Profiles on the progress of spinal extradural anaesthesia were made in 246 patients using various concentrations of lignocaine, bupivacaine and etidocaine. The advance of analgesia through the different dermatomes showed a consistent and orderly spread on the upper lumbar and thoracic segments. This spread was irregular through the lower lumbar and upper sacral segments. The first sacral segment was especially difficult to block with an overall failure rate of 17.53% with presently available concentrations of … Show more

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Cited by 66 publications
(30 citation statements)
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“…1 Of the 40 patients in our previous study, only 15 (38%) experienced loss of cold sensation in the S1 dermatome with 33 (83%) reporting loss in the S3 dermatome. 2 However, even in cases of incomplete epidural blockade of the sacral nerves, we often encounter patients who do not complain of unpleasant sensations or pain upon undergoing invasive urogenital or rectal procedures that are expected to cause pain.…”
mentioning
confidence: 74%
“…1 Of the 40 patients in our previous study, only 15 (38%) experienced loss of cold sensation in the S1 dermatome with 33 (83%) reporting loss in the S3 dermatome. 2 However, even in cases of incomplete epidural blockade of the sacral nerves, we often encounter patients who do not complain of unpleasant sensations or pain upon undergoing invasive urogenital or rectal procedures that are expected to cause pain.…”
mentioning
confidence: 74%
“…This is in line with other studies where only high local anesthetic concentrations produced a complete sensory block of L 5 and S 1 roots [13][14][15][16] . This is because L 5 and S 1 roots are thicker, thus prolonging sensory and motor block onset and decreasing their intensity 17 . In a previous study, 0.5% bupivacaine, associated or not to epidural or intravenous fentanyl, has not provided total anesthesia and immobility in the territory innervated by L 4 , L 5 and S 1 roots 18 .…”
Section: Discussionmentioning
confidence: 99%
“…Embora a concentração eficaz em 95% dos pacientes (CE 95 ) seja mais relevante para a prática clínica, a concentração eficaz em 50% dos pacientes (CE 50 ) é uma ferramenta mais útil de pesquisa, dada a sua posição na curva de concentra- -16 . A razão para isto é que as raízes de L 5 e S 1 são mais calibrosas, o que prolonga a latência do bloqueio sensitivo e motor e diminui sua intensidade 17 . Em estudo anterior, a bupivacaína a 0,5%, associada ou não ao fentanil por via peridural ou venosa, não proporcionou anestesia completa e imobilidade no território inervado pelas raízes L 4 , L 5 e S 1 18 .…”
Section: Estudo Iunclassified
“…Fifteen millilitre provides good anaesthesia to the large nerve trunks L5 and SI, with minimal circulatory compromise. Lesser doses may not anaesthetize these nerve roots adequately (Galindo, et al, 1975).…”
Section: Discussionmentioning
confidence: 99%