Quality of Survival in Children and Adolescents After Treatment for Childhood Cancer: The Influence of Reported Late Effects on Health Related Quality of Life

Abstract

Our results underline the influence of objective long term effects and subjective QoL on the Quality of Survival. Prospective evaluation will lead to new and important information with respect to the onset of somatic and psychosocial LF and possible coping strategies. These information will establish additional possibilities for initiation of primary and secondary rehabilitation processes.

Quality of life in children and adolescents surviving cancer

“…These results emphasise the need for addressing the issue of diagnosis and presence of late effects in QoL studies in childhood cancer survivors. Our results are consistent with other studies of reduced QoL among children surviving brain tumours (Upton et al, 2005;Cardarelli et al, 2006;Varni et al, 2007;Penn et al, 2009;Yoo et al, 2010), as well as among studies and reviews of late effects and QoL of childhood cancer (Pemberger et al, 2005;Calaminus et al, 2007;Eiser et al, 2007;Ishida et al, 2010a, b).…”

Late Effects of Thoracic Irradiation in Children

“…In Germany, several study groups examine different aspects of late effects [10,23]. In the USA, the Childhood Cancer Survivor Study has been established to retrospectively characterize the health status of 5-year survivors of childhood cancer [20,28].…”

Die deutsche Kohorte Langzeitüberlebender nach Krebs im Kindesalter

“…Neben dem DKKR haben noch drei andere, sich ebenfalls mit Spätfolgen befassende Arbeitsgruppen eine zentrale Bedeutung für die deutsche pädiatrische Onkologie und Häma-tologie. Dies sind die LESS-Gruppe (LateEffects-Surveillance-System) für durch Chemotherapie bedingte Spätfolgen [13], die RISK-Gruppe (Register zur Erfassung von Spätfolgen nach Strahlentherapie im Kindes-und Jugendalter) für durch Radiotherapie bedingte Spätfolgen [14] sowie eine Lebensqualitäts-Gruppe [15].…”