A novel high-impedance compound film material has been developed to satisfy the reservoir of many kinds of space liquid in space station. Considering the high gas-resistance and liquid-resistance, and its compatibility with the liquid in space station, the complex film was designed using 9 layers materials. The compatibility experiment and mechanical properties experiment showed that the high-impedance complex film has good compatibility with drinking water in space station. It also has excellent heat seal ability, physical and mechanical properties. The complex film also has high gas-resistance and water-resistance property, as well as great chemical corrosion-resistance property. The high-impedance complex film material offers a new method for the design and application of liquid container in space station.