Quantification of hepatic arterial and portal perfusion with dynamic computed tomography: comparison of maximum-slope and dual-input one-compartment model methods

Abstract

Except for HAP with arterial injection, the perfusion parameters obtained with the MS method were lower than those obtained with the DOCM method.

Hepatic computed tomography perfusion: comparison of maximum slope and dual-input single-compartment methods

“…These fi ndings are consistent with previously reported results. 17,18 However, HAP and APF showed moderate correlation, and HPP showed poor correlation for the two methods in our study, whereas previous studies reported signifi cant correlations. One possible reason for this discrepancy was the relatively low injection rate used in our study (5 ml/s), which may have weakened the assumption of "no venous outfl ow" for the MS method and thus could have affected our results.…”

“…One study, for example, used a much higher rate of 8 ml/s. 18 In routine clinical use, such a high rate can produce severe "hot fl ushes" in the patient, which can cause motion artifacts and increase the failure rate of venous access. In addition, previous reports were retrospective assessments of small populations.…”

Feasibility of Measuring Human Pancreatic Perfusion In Vivo Using Imaging Techniques

“…We reviewed the dynamic CT data obtained in our previous study 4 and selected the patients in whom the pancreas was included in the dynamic CT sequence. Institutional review board approval was obtained, and all patients gave their written informed consent to participate in this study.…”

“…The detailed principles of these methods have been discussed elsewhere. 2,4 Perfusion is calculated as the concentration of contrast media in the tissue divided by the difference between total amount of contrast media that has flowed into the tissue and the amount of contrast media that has flowed out of the tissue:…”

The evaluation of haemodynamics in cirrhotic patients with spectral CT

“…At present, a CT liver perfusion scan is one of the imaging means to obtain liver haemodynamics. Perfusion parameters, such as liver blood volume, blood flow (BF), mean transit time (MTT) and hepatic perfusion index (HPI), can be obtained by perfusion scans using the cine mode or dynamic shuttle mode and mathematic calculations [2][3][4]. Liver haemodynamic changes in cirrhotic patients with portal hypertension can be detected by calculating the liver perfusion parameters, including decreasing liver BF and increasing liver HPI, that are related to decreased liver function [1,5].…”