2012
DOI: 10.1007/s10295-012-1090-4
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Quantification of metabolism in Saccharomyces cerevisiae under hyperosmotic conditions using elementary mode analysis

Abstract: Yeast metabolism under hyperosmotic stress conditions was quantified using elementary mode analysis to obtain insights into the metabolic status of the cell. The fluxes of elementary modes were determined as solutions to a linear program that used the stoichiometry of the elementary modes as constraints. The analysis demonstrated that distinctly different sets of elementary modes operate under normal and hyperosmotic conditions. During the adaptation phase, elementary modes that only produce glycerol are activ… Show more

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Cited by 4 publications
(1 citation statement)
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“…Cyanide, in its solid form, is combined with various metal ions such as potassium and sodium to form white crystalline substances, which are stable. It was hypothesized that cyanide was the first organic compound on earth, from which chemical compounds are formed (Oparin, 1957;Rawls, 1997;Parmar et al, 2012).…”
Section: Introductionmentioning
confidence: 99%
“…Cyanide, in its solid form, is combined with various metal ions such as potassium and sodium to form white crystalline substances, which are stable. It was hypothesized that cyanide was the first organic compound on earth, from which chemical compounds are formed (Oparin, 1957;Rawls, 1997;Parmar et al, 2012).…”
Section: Introductionmentioning
confidence: 99%