Quantification of regional contractile function after infarction: strain analysis superior to wall thickening analysis in discriminating infarct from remote myocardium

Götte, Marco J.W.; Rossum, Albert C. van; Twisk, Jos W. R.; Kuijer, Joost P.A.; Marcus, J. Tim; Visser, Cees A.

doi:10.1016/s0735-1097(00)01186-4

Cited by 171 publications

(114 citation statements)

References 36 publications

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“…2 and 4. This finding is consistent with a previous report, which showed circumferential strain to be more sensitive to the presence of myocardial infarction than wall thickening (8).…”

Section: Relationship Between Scar Extent and Circumferential Strainsupporting

confidence: 93%

Relationship Between the Extent of Non-viable Myocardium and Regional Left Ventricular Function in Chronic Ischemic Heart Disease

Kolipaka¹,

Chatzimavroudis²,

White³

et al. 2005

J. of Cardiovascular Magnetic Resonance

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Follow this and additional works at: http://engagedscholarship.csuohio.edu/encbe_facpub Part of the Biochemical and Biomolecular Engineering Commons, and the Biomedical Engineering and Bioengineering Commons How does access to this work benefit you? Let us know! Repository CitationKolipaka, Arunark; Chatzimavroudis, George P.; White, Richard D.; Lieber, Michael L.; and Setser, Randolph M., "Relationship between the extent of non-viable myocardium and regional left ventricular function in chronic ischemic heart disease" (2005 Purpose. To define the relationship between left ventricular ( LV) regional contractile function and the extent of myocardial scar in patients with chronic ischemic heart disease and multi-vessel coronary artery disease. Methods. Twenty-three patients with chronic ischemic heart disease and 5 healthy volunteers underwent magnetic resonance imaging ( MRI). In patients, the relative area ( Percent Scar) and transmural extent ( Transmurality) of myocardial infarction were computed from short-axis delayed enhancement images. In each image, myocardial segments were categorized based on the extent of infarction they contained, with 6 categories each for Percent Scar and Transmurality: normal, from healthy volunteers; and 0%; 1 -25%, 26 -50%, 51 -75%, and > 76% from patients. In patients and volunteers, regional LV function was quantified by absolute systolic wall thickening from cine images and midwall circumferential strain using tagged images.Results. Compared to normal segments, regional LV function in patients was significantly diminished in all scar extent intervals, with wall thickening 1 mm and strain !À8% for all categories. Systolic wall thickening was reduced significantly in all categories above 50% Percent Scar and above 25% Transmurality in patients, relative to corresponding 0% categories. Circumferential strain was significantly reduced above 25% Percent Scar and above 25% Transmurality. Conclusions. In patients with chronic ischemic heart disease and multivessel coronary artery disease, wall thickening was more sensitive to changes in scar Transmurality than to changes in Percent Scar. However, circumferential strain was equally sensitive to both indices. In general, circumferential strain was more sensitive than wall thickening to increases in scar extent.

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“…2 and 4. This finding is consistent with a previous report, which showed circumferential strain to be more sensitive to the presence of myocardial infarction than wall thickening (8).…”

Section: Relationship Between Scar Extent and Circumferential Strainsupporting

confidence: 93%

Relationship Between the Extent of Non-viable Myocardium and Regional Left Ventricular Function in Chronic Ischemic Heart Disease

Kolipaka¹,

Chatzimavroudis²,

White³

et al. 2005

J. of Cardiovascular Magnetic Resonance

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“…Resting LV dysfunction can be precisely assessed by use of cine acquisitions with tissue tagging and strain analysis (52). As with echocardiography, the assessment of LV enddiastolic wall thickness is useful for ruling out viability.…”

Section: Mrimentioning

confidence: 99%

Assessment of Myocardial Viability in Patients with Heart Failure

Schinkel¹,

Poldermans²,

Elhendy³

et al. 2007

Journal of Nuclear Medicine

134

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The prognosis for patients with chronic ischemic left ventricular dysfunction is poor, despite advances in different therapies. Noninvasive assessment of myocardial viability may guide patient management. Multiple imaging techniques have been developed to assess viable and nonviable myocardium by evaluating perfusion, cell membrane integrity, mitochondria, glucose metabolism, scar tissue, and contractile reserve. PET, 201 Tl and 99m Tc scintigraphy, and dobutamine stress echocardiography have been extensively evaluated for assessment of viability and prediction of clinical outcome after coronary revascularization. In general, nuclear imaging techniques have a high sensitivity for the detection of viability, whereas techniques evaluating contractile reserve have a somewhat lower sensitivity and a higher specificity. MRI has a high diagnostic accuracy for assessment of the transmural extent of myocardial scar tissue. Patients with a substantial amount of dysfunctional but viable myocardium are likely to benefit from coronary revascularization and may show improvements in regional and global contractile function, symptoms, exercise capacity, and long-term prognosis.

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“…20 Quantitative assessment of contractile function by magnetic resonance (MR) tissue tagging and strain analysis suggested that strain could accurately detect dysfunctional myocardium, with a cutoff value of -20%. 21 Reisner et al developed and validated the AFI algorithm to assess global LV function, and demonstrated a strong linear correlation between WMSI and GLS with R 2 = 0.55. 12 Our results show good agreement with theirs.…”

Section: Comparison Of Gls With Results Obtained Using Other Methodsmentioning

confidence: 99%

Validation of Longitudinal Peak Systolic Strain by Speckle Tracking Echocardiography With Visual Assessment and Myocardial Perfusion SPECT in Patients With Regional Asynergy

Kusunose

Yamada

Nishio

et al. 2011

Circ J

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Quantification of regional contractile function after infarction: strain analysis superior to wall thickening analysis in discriminating infarct from remote myocardium

Abstract: Two-dimensional strain analysis is more accurate than planar WT analysis in discriminating dysfunctional from functional myocardium, and it provides a strong correlation between regional myocardial and global ventricular function.

Cited by 171 publications

References 36 publications

Relationship Between the Extent of Non-viable Myocardium and Regional Left Ventricular Function in Chronic Ischemic Heart Disease

Relationship Between the Extent of Non-viable Myocardium and Regional Left Ventricular Function in Chronic Ischemic Heart Disease

Assessment of Myocardial Viability in Patients with Heart Failure

Validation of Longitudinal Peak Systolic Strain by Speckle Tracking Echocardiography With Visual Assessment and Myocardial Perfusion SPECT in Patients With Regional Asynergy

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