Quantification of the drawing of an Archimedes spiral through the analysis of its digitized picture

Miralles, Francesc; Tarongí, S.; Espino, A.

doi:10.1016/j.jneumeth.2005.08.007

Cited by 61 publications

(31 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, some alterations and aggravations can amplify tremor making it visible, like stress situations, anxiety, muscular fatigue, and the use of certain drugs. 5,32 Most studies found in literature are related to the analysis of pathological tremor, 1,8,10,12,13,15,17,20,24,28,30,35 highlighting the lack of investigations aiming to understand the complex relation between physiological tremor and aging, specifically in kinetic conditions. 11,23,25,29,33 The most common methods for measuring tremor are through the analysis of accelerometry and electromyography.…”

Section: Introductionmentioning

confidence: 99%

“…10,11,25,29,33,34 Another common method to analyze it is by means of the study of handdrawing movements. 12,13,15,17,24,28,30,35 This kind of analysis makes possible the study of the kinetic tremor, which occurs during voluntary movement.…”

Section: Introductionmentioning

confidence: 99%

“…In this study, the selected drawing pattern is the spiral of Archimedes as it is the gold-standard in neurological assessments. [11][12][13]15,17,20,24,30,35 Several attributes of the spiral of Archimedes make its use attractive in tests for the detection of human tremor. First, it has a simple design and it is easily understood by subjects who can follow its trajectory.…”

Section: Introductionmentioning

confidence: 99%

“…[12][13][14][15]17,20,24,30,35 However, even with the advances in the technology of digitizing tablets, which allowed for more precision and accuracy in the measurement of movements, no study focusing upon the use of these devices, as a tool for investigating the relation between physiological tremor and aging in kinetic conditions, was found in our literature survey. Although some authors, e.g., Wenzelburger et al, 36 support the hypothesis that kinetic tremor is related to an enhancement of physiological tremor this assumption is not consensual 11,29,33 and therefore additional studies in this area are required.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Investigation of Age-Related Changes in Physiological Kinetic Tremor

et al. 2010

View full text Add to dashboard Cite

Tremor is the most common movement disorder characterized by repetitive and stereotyped movements. Most investigations on tremor attempt to understand its relation to neuromuscular dysfunctions. Therefore, there is a lack of studies that aim to investigate the complex relation between the physiological tremor and aging, especially in kinetic conditions. In this context, the main motivation of this research was to quantify age-related changes in the kinetic tremor of clinically healthy individuals. For this, a number of features extracted from tremor activity, obtained from digitized drawings of Archimedes' spirals, were analyzed. In total, 59 subjects participated in the experiments. These individuals were divided into seven groups according to their ages and two types of analysis were carried out. First, the tremor activity of young and elderly adults was investigated by means of traditional features commonly used in tremor analysis, and secondly, linear discriminant analysis (LDA) was employed for the study of the correlation between age and tremor. The results showed significant statistical differences between the kinetic tremor activity of the young and elderly groups. Furthermore, it was found that LDA allowed for the estimate of a unique feature, so-called LDA-value, which showed to be linearly correlated with age.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Investigation of Age-Related Changes in Physiological Kinetic Tremor

et al. 2010

View full text Add to dashboard Cite

show abstract

“…The subjects were asked to draw two samples of a Spiral of Archimedes with their dominant hand and then stood still. The first sample was collected with the subject drawing the spiral from its centre to its extremity (outgoing spiral -OS), whereas for the second sample the subject drew the spiral from its extremity to its centre (ingoing spiral -IS), and the third sample was collected with the subject stood still (standing still -S) pointing the laser to the center of the spiral (Miralles et al, 2006). This procedure was repeated three times for each subject and each collection time was approximately 30 seconds.…”

Section: Methodsmentioning

confidence: 99%

Analysis of the relationship between EEG signal and aging through Linear Discriminant Analysis (LDA)

Paiva¹,

Pereira²,

Almeida³

et al. 2012

RBEB

View full text Add to dashboard Cite

This paper aims to establish the correlation between statistical parameters and Electroencephalographic (EEG) signals as a function of age, in subjects without neurological disorders. EEG signals were recorded during the task of following an Archimedes spiral. There were 59 healthy subjects who voluntarily participated in this study which were divided into 7 groups, aging between 20 to 86 years from both gender, in order to identify differences and allow discrimination between the features of each group. Initially, comparisons were made among several features (F20, F50, F80, F95, Mean Frequency, Root Mean Square value, Zero Crossings, Square of the Power Spectrum, Kurtosis, Skewness, Variance, Standard Deviation and Approximate Entropy) seeking separation between young and elderly groups. Furthermore, it was sought to correlate the statistical parameters and the entire age range. For this purpose it was used Linear Discriminant Analysis (LDA). The data were processed with MATLAB ® software. Through the LDA, significant differences were observed over the distinct age ranges. The tool has satisfactorily performed the separation of discriminant features by classifying groups of subjects in function of their age range.Keywords Electroencephalography, Linear Discriminant Analysis, Aging. Análise das relações entre o sinal EEG e o envelhecimento através da Análise Discriminante Linear (ADL)Resumo

show abstract

Quantitative evaluation of the drawing of a spiral on a paper

2011

View full text Add to dashboard Cite

We have read with interest the study by Santangelo et al., 1 reporting the role of vascular pathology in the neuropsychological profile of parkinsonian patients. The authors evaluated whether the brain's vascular lesion load is associated with neuropsychological variables. They compared the neuropsychological profile of patients affected by Parkinsonism and vascular lesions to that of patients with Parkinson's disease (PD) without vascular lesions. The conclusion was that ''regardless of the presence of dopaminergic denervation, cerebrovascular lesions . . . have an important effect in determining early onset and severity of cognitive impairment in patients with parkinsonism''. We agree with the authors that a comorbid cerebrovascular disease (CVD) may have an important impact on impairment of cognitive functions in patients with PD. In this aspect, the PD patients are not fundamentally different from patients without Parkinsonism.We have recently demonstrated that the pathology of vessels supplying the brain contribute to the disease severity in PD patients even without a CVD. 2 In 57 consecutive PD patients, we measured ultrasound parameters indicating an atherosclerotic disease of the large and small brain vessels. The occurrence of the MRI and clinically manifested CVD was rare (stroke or transient ischemic attack in five patients, only small volume white matter lesions), concurring with results of large epidemiological studies. 3,4 The ultrasonographic examination of extracranial vessels comprised the measurement of the intima-medial thickness (IMT) of the common carotid artery, and the carotid arteries were evaluated for the presence of atherosclerotic plaques. IMT is considered to be a useful sonographic marker of early atherosclerotic affection. Regarding the ultrasonographic examination of intracranial vessels, the resistance and pulsatility indexes (RI, PI) were calculated. These indexes are not just functions of flow resistance; they are also influenced by vascular compliance. The results of a multiple regression analysis revealed a significant association between the IMT and motor, functional, and cognitive impairment (as measured by the Hoehn-Yahr score, Lawton's Instrumental Activities of Daily Living, Barthel Index, Mini-Mental State Examination, and Clock Drawing Test -for details see Rektor et al. 2 ). Several cognitive tests (Benton Temporal Orientation Test and the Recognition subtest of the Wechsler Memory Scale III) were significantly associated with the PI.Our results suggest a possible link between a comorbid and otherwise subclinical atherosclerotic involvement and the degree of motor and cognitive decline caused primarily by disease-related degenerative brain changes. This subclinical brain hypoperfusion may affect the severity of clinical symptoms of PD even prior to the development of CVD. Z, Dufek M. Vascular pathology in patients with idiopathic Parkinson's disease. Parkinsonism Rel Disord 2009;5:24-29. 3. Sławek J, Wieczorek D, Derejko M, et al. The influence of vascular risk factors...

show abstract

Quantification of the drawing of an Archimedes spiral through the analysis of its digitized picture

Cited by 61 publications

References 10 publications

Investigation of Age-Related Changes in Physiological Kinetic Tremor

Investigation of Age-Related Changes in Physiological Kinetic Tremor

Analysis of the relationship between EEG signal and aging through Linear Discriminant Analysis (LDA)

Quantitative evaluation of the drawing of a spiral on a paper

Contact Info

Product

Resources

About