Quantification of the xenoestrogens 4-tert.-octylphenol and bisphenol A in water and in fish tissue based on microwave assisted extraction, solid-phase extraction and liquid chromatography–mass spectrometry

Pedersen, Søren N.; Lindholst, Christian

doi:10.1016/s0021-9673(99)01011-0

Cited by 149 publications

(56 citation statements)

References 19 publications

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“…Bisphenol A was also detected in saliva after dental treatment with epoxy resins (Olea et al 1996). Conjugated bisphenol A has been identified in the rainbow trout exposed to sewage plant effluent (Larsson et al 1999;Pedersen & Lindholst 1999). The oestrogenicity of bisphenol A has been demonstrated in a number of in vitro assays (Krishnan et al 1993;Soto et al 1995; Author for correspondence: Christel Moraeus Olsen, The Norwegian Institute of Public Health, P. O.…”

mentioning

confidence: 99%

Effects of the Environmental Oestrogens Bisphenol A, Tetrachlorobisphenol A, Tetrabromobisphenol A, 4‐Hydroxybiphenyl and 4,4′‐Dihydroxybiphenyl on Oestrogen Receptor Binding, Cell Proliferation and Regulation of Oestrogen Sensitive Proteins in the Human Breast Cancer Cell Line MCF‐7

Olsen¹,

Meussen‐Elholm²,

Samuelsen³

et al. 2003

Pharmacology & Toxicology

108

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Bisphenol A is extensively used in the manufacturing of epoxy resins and polycarbonate plastics, whereas several brominated and chlorinated analogues are used as flame retardants and intermediates in the plastic industry. Due to the structural relationship between these chemicals and the high production volumes, we wanted to characterize and compare their potential oestrogen-like potency using several end-points in MCF-7 cells: induction of pS2 protein and progesterone receptor, reduction of oestrogen receptor level, and stimulation of cell growth. Bisphenol A, tetrachloro-and tetrabromobisphenol A, 4-hydroxybiphenyl and 4,4ø-dihydroxybiphenyl all showed oestrogen-like properties in MCF-7 cells. The chemicals tested had affinity to the oestrogen receptor isolated from MCF-7 cells, although their EC 50 s were 1,000 to 80,000 times higher than the EC 50 of 17b-oestradiol. Bisphenol A and 4-hydroxybiphenyl induced cell growth in MCF-7 cells, and the highest test concentrations induced responses, apparently exceeding the cell growth induced by 17b-oestradiol. The other chemicals tested induced less than 50% of the maximum 17b-oestradiol-stimulated cell growth. Bisphenol A, 4-hydroxybiphenyl, tetrabromobisphenol A and tetrachlorobisphenol A all increased the level of the oestrogen-regulated proteins, progesterone receptor and pS2, whereas 4,4ø-dihydroxybiphenyl showed no such effect. Bisphenol A was the only chemical tested that clearly mimicked 17b-oestradiol in its ability to reduce the level of cytosolic oestrogen receptors in MCF-7 cells. By measuring several oestrogen-dependent endpoints it seems that some xeno-oestrogens cause an imbalanced oestrogen-response. Their ability and potency in mimicking 17b-oestrogen in one parameter is not necessarily accompanied by a similar effect in another oestrogen-linked parameter.

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mentioning

confidence: 99%

Effects of the Environmental Oestrogens Bisphenol A, Tetrachlorobisphenol A, Tetrabromobisphenol A, 4‐Hydroxybiphenyl and 4,4′‐Dihydroxybiphenyl on Oestrogen Receptor Binding, Cell Proliferation and Regulation of Oestrogen Sensitive Proteins in the Human Breast Cancer Cell Line MCF‐7

Olsen¹,

Meussen‐Elholm²,

Samuelsen³

et al. 2003

Pharmacology & Toxicology

108

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“…For this purpose the most often used methods are liquid-liquid extraction [20][21][22], Soxhlet extraction [3,23], solid phase extraction [6,22,, membrane extraction [45][46][47], accelerated solvent extraction [7,13,[48][49][50][51][52][53][54], ultrasonic assisted extraction [32,[55][56][57][58], microwave assisted extraction [59][60][61], stir-bar sorptive extraction [4,[62][63][64][65][66][67][68][69], matrix solid phase dispersion [70][71][72][73][74] …”

Section: Extraction Methods Of Bisphenols and Alkylphenols From Envirmentioning

confidence: 99%

“…The resulting extract was next purified onto Sep-Pak NH 2 cartridges. Values of recovery of analytes from spiked liver and muscle tissue determined by LC-MS were between 47-79% [60].…”

Section: Microwave Assisted Extraction (Mae)mentioning

confidence: 99%

Extraction Techniques for Isolation, Purification and Preconcentration of Bisphenols and Alkylphenols from Environmental and Food Samples

Arivoli¹,

Arasakumar²

2017

International Journal of Advanced Research in Chemical Science

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“…Some sample preconcentration procedures were applied for the pretreatment of BPA-containing samples, such as, single-drop liquid-phase microextraction (SDME) [6], solid-phase extraction (SPE) [7][8][9], liquid-liquid extraction (LLE) [10], stir bar sorptive extraction (SBSE) [11], solid-phase microextraction (SPME) [12,13], liquid-phase microextraction (LPME) [14], and molecularly imprinted solid-phase extraction (MISPE) [15,16]. Recently, a new microextraction method, named dispersive liquid-liquid microextraction (DLLME), introduced by Assadi et al [17], has been used as a powerful preconcentration technique for extraction of verity compounds including BPA [18][19][20][21][22][23][24][25][26][27].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of alcoholic-assisted dispersive liquid-liquid microextraction of bisphenol a in water samples using an experimental design

Fatemi

Hadjmohammadi

Shakeri

2014

Acta Chromatographica

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Summary. Alcoholic-assisted dispersive liquid-liquid microextraction method (AA-DLLME) is used for the extraction, purification, and determination of bisphenol A in water samples by HPLC-UV. 1-octanol and methanol were selected as extraction and dispersive solvents of AA-DLLME procedure. The effects of several parameters of the AA-DLLME procedure (such as volume of extraction and dispersive solvents, amount of salt in sample solution, and extraction time) were investigated by a full factorial design. Then, the levels of significant factors were optimized using a central composite facecentered. The optimum conditions were obtained at 158 μL of extraction solvent, 500 μL of dispersive solvent, 1 min extraction time, and addition of 22% (w/v) of NaCl to the sample solution. Under optimum condition, the extraction recovery and the enrichment factor were determined, which were 91% and 65%, respectively. At these conditions, the limit of detection and the linearity were 0.10 and 1-100 μg L −1 , respectively. The relative standard deviations for intra-and inter-day of extraction of bisphenol A (BPA) were 6.98% and 9.80%, respectively (for five measurements). Finally, the method was successfully applied for the determination of BPA in environmental water samples. In conclusion, it can be stated that the applied method is fast, simple, and environmentally friendly.

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Quantification of the xenoestrogens 4-tert.-octylphenol and bisphenol A in water and in fish tissue based on microwave assisted extraction, solid-phase extraction and liquid chromatography–mass spectrometry

Cited by 149 publications

References 19 publications

Effects of the Environmental Oestrogens Bisphenol A, Tetrachlorobisphenol A, Tetrabromobisphenol A, 4‐Hydroxybiphenyl and 4,4′‐Dihydroxybiphenyl on Oestrogen Receptor Binding, Cell Proliferation and Regulation of Oestrogen Sensitive Proteins in the Human Breast Cancer Cell Line MCF‐7

Effects of the Environmental Oestrogens Bisphenol A, Tetrachlorobisphenol A, Tetrabromobisphenol A, 4‐Hydroxybiphenyl and 4,4′‐Dihydroxybiphenyl on Oestrogen Receptor Binding, Cell Proliferation and Regulation of Oestrogen Sensitive Proteins in the Human Breast Cancer Cell Line MCF‐7

Extraction Techniques for Isolation, Purification and Preconcentration of Bisphenols and Alkylphenols from Environmental and Food Samples

Evaluation of alcoholic-assisted dispersive liquid-liquid microextraction of bisphenol a in water samples using an experimental design

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