Quantifying Effects of Retinal Illuminance on Frequency Doubling Perimetry

Swanson, William H.; Dul, Mitchell W.; Fischer, Susan E.

doi:10.1167/iovs.04-0264

Cited by 14 publications

(19 citation statements)

References 18 publications

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“…13 The temporal presentation for Gabor stimuli was a 600-msec increment in contrast, with abrupt onset and offset of 5-Hz counterphase square-wave flicker. A temporal frequency of 5 Hz was chosen to avoid effects of reduced retinal illumination that affect frequency-doubling perimetry, 40,41 and abrupt onset and offset were used to maximize the temporal contrast.…”

Section: Perimetrymentioning

confidence: 99%

Choice of Stimulus Range and Size Can Reduce Test-Retest Variability in Glaucomatous Visual Field Defects

Swanson

Horner

Dul

et al. 2014

Trans. Vis. Sci. Tech.

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Purpose: To develop guidelines for engineering perimetric stimuli to reduce testretest variability in glaucomatous defects.Methods: Perimetric testing was performed on one eye for 62 patients with glaucoma and 41 age-similar controls on size III and frequency-doubling perimetry and three custom tests with Gaussian blob and Gabor sinusoid stimuli. Stimulus range was controlled by values for ceiling (maximum sensitivity) and floor (minimum sensitivity). Bland-Altman analysis was used to derive 95% limits of agreement on test and retest, and bootstrap analysis was used to test the hypotheses about peak variability.Results: Limits of agreement for the three custom stimuli were similar in width (0.72 to 0.79 log units) and peak variability (0.22 to 0.29 log units) for a stimulus range of 1.7 log units. The width of the limits of agreement for size III decreased from 1.78 to 1.37 to 0.99 log units for stimulus ranges of 3.9, 2.7, and 1.7 log units, respectively (F ¼ 3.23, P , 0.001); peak variability was 0.99, 0.54, and 0.34 log units, respectively (P , 0.01). For a stimulus range of 1.3 log units, limits of agreement were narrowest with Gabor and widest with size III stimuli, and peak variability was lower (P , 0.01) with Gabor (0.18 log units) and frequency-doubling perimetry (0.24 log units) than with size III stimuli (0.38 log units).Conclusions: Test-retest variability in glaucomatous visual field defects was substantially reduced by engineering the stimuli.Translational Relevance: The guidelines should allow developers to choose from a wide range of stimuli.

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Section: Perimetrymentioning

confidence: 99%

Choice of Stimulus Range and Size Can Reduce Test-Retest Variability in Glaucomatous Visual Field Defects

Swanson

Horner

Dul

et al. 2014

Trans. Vis. Sci. Tech.

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“…Swanson et al [33] have shown that FDT perimetry depends critically on retinal illuminance. In our sample of participants, pupil area ranged from 7.6 to 32.…”

Section: Pupil Areamentioning

confidence: 99%

Novel electrophysiological instrument for rapid and objective assessment of magnocellular deficits associated with glaucoma

et al. 2008

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“…10 The use of high temporal frequencies makes FDP susceptible to the effects of reduced retinal illumination, due to factors such as pupillary miosis and increase in lens density. 11 The goal of the present study was to design a new perimetric protocol, by using contrast sensitivity perimetry (CSP), 12 which could improve clinical management of glaucoma by building on findings of these earlier studies. We used a stimulus with a peak spatial frequency in the range used by FDP, but without the sharp stimulus edges and high temporal frequencies used in FDP.…”

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confidence: 99%

Development and Evaluation of a Contrast Sensitivity Perimetry Test for Patients with Glaucoma

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Dul

Swanson

2008

Invest. Ophthalmol. Vis. Sci.

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Quantifying Effects of Retinal Illuminance on Frequency Doubling Perimetry

Abstract: The results confirmed previous findings that FDT perimetry can be dramatically affected by variations in retinal illuminance. Application of a quantitative adaptation model provided guidelines for estimating effects of pupil diameter and lens density on FDT perimetry.

Cited by 14 publications

References 18 publications

Choice of Stimulus Range and Size Can Reduce Test-Retest Variability in Glaucomatous Visual Field Defects

Choice of Stimulus Range and Size Can Reduce Test-Retest Variability in Glaucomatous Visual Field Defects

Novel electrophysiological instrument for rapid and objective assessment of magnocellular deficits associated with glaucoma

Development and Evaluation of a Contrast Sensitivity Perimetry Test for Patients with Glaucoma

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