Quantifying losses to the donated blood supply due to donor deferral and miscollection

Custer, Brian; Johnson, Eric S.; Sullivan, Sean D.; Hazlet, Tom K.; Ramsey, Scott D.; Hirschler, Nora V.; Murphy, Edward L.; Busch, Michael P.

doi:10.1111/j.1537-2995.2004.04160.x

Cited by 107 publications

(139 citation statements)

References 23 publications

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“…Our findings (36.3%) were much higher than Custer et al [7] who reported a permanent deferral rate of 10.6% and Arslan [9] who reported a rate of 10%. This high frequency was due to the inclusion of transfusion transmissible infection in our study especially Hepatitis B infection (HBV) which was not studied thoroughly in the above mentioned publications.…”

Section: Resultscontrasting

confidence: 55%

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The Evaluation of Blood Donor Deferral Causes: A Tertiary Care CentrebasedStudy

Rehman¹

2013

J Blood Disord Transfus

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Blood safety is a major issue all over the world in transfusion medicine. For this, donor selection is necessary in addition to the screenings of blood bags for infectious diseases. Deferrals lead to loss of precious blood/ components available for transfusion. For preventing this, we should be having knowledge of causes of deferral and their frequency. In this study, causes of donor deferral were evaluated retrospectively from January 2007 to December 2011 in the blood bank of Jawaharlal Nehru Medical College (JNMC), Aligarh Muslim University (AMU), ALIGARH (India). Analysis of the deferrals showed that temporary deferral was more common than permanent deferral. Most common cause in permanent deferral was HBsAg positivity. Causes among temporary deferral were anemia (Hb<12.5 gm%), malaria in last 3 months, jaundice, alcohol intake in last 3days, weight <45 kg, age <18 yrs, patients on antibiotic, previous donation in last 3 month, typhoid in last 1 year, dog bite etc.

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Section: Resultscontrasting

confidence: 55%

“…Zou et al [6] reported a deferral rate of 12.8% in their 6 years study of American Red Cross blood service and Custer et al [7] showed a deferral rate of 13.6%. In a European study conducted by Lawson-Ayayi and Salmi [8], 10.8% of donors were deferred.…”

Section: Discussionmentioning

confidence: 99%

The Evaluation of Blood Donor Deferral Causes: A Tertiary Care CentrebasedStudy

Rehman¹

2013

J Blood Disord Transfus

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“…Most of the deferrals (66.6%) were due to temporary causes such as anemia, medication, tattooing, previous donation less than three months ago as compared to permanent deferral causing 33.3% Custer et al reported 68.5% temporary and 31.5% permanent deferral [8]. Such temporarily deferred donors can be motivated to return back after proper education about deferral criteria.…”

Section: Discussionmentioning

confidence: 99%

Pre Donation Deferral a Single Centre Experience

Vasudev¹,

Kaur²

2016

J Blood Disord Transfus

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It is well known that quite a large number of apparently healthy donors are not able to donate blood successfully because of varied reasons. These donors are deferred temporarily or permanently. The aim of the study was to analyze the Incidence of Blood Donor deferral and its various causes and use this information as a guide for promoting Voluntary Blood donation. All the Blood donors reporting at our Blood Bank in last 6 months period were analyzed retrospectively. Data of all the donors deferred due to various causes was analyzed at our Transfusion Medicine Centre. There were 7253 donors, of which 524 donors were deferred (7.22%) for various reasons. Of the 7253 donors registered for donation, females constituted only 8.6%. And deferral rate was about six times more for female (29.05%) compared to male (5.18%). The three most common reasons for deferral low hemoglobin levels, chronic diseases and medication. More studies should be done at state and national level so that enough data can be collected and national policies formulated and western parameters for deferral should not be followed as regional differences cause unnecessary deferrals of already limited donors. Moreover analysis of donor deferral pattern will help blood banks to formulate more focused donor screening approach.

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“…More number of deferral was in temporary constituting 83.11% and permanent 16.89%. Custer et al [7] report 68.5% temporary and 31.5% permanent deferral [7]. In our study permanent deferral constituted only 16.89% which may be due to more number of younger donors.…”

Section: Discussionmentioning

confidence: 38%

“…In our study the unsuccessful phlebotomy was only 0.31%. Whereas Farrales et al [10] reported a higher rate of 0.5% and Custer et al [7] reported mis-collection leading to 3.8% of 1001,141 collections. The deferral for young people would be different from the reasons for older ones.…”

Section: Discussionmentioning

confidence: 93%

Whole Blood Donor Deferral Causes in a Tertiary Care Teaching Hospital Blood Bank from South India

Basavarajegowda¹

2017

HTIJ

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Introduction: Suspension of eligibility of an individual to donate blood or blood components due to various causes is called deferral. This is intended to take care that removal of blood does not harm the donor and that the potential risk to the recipient due to disease conditions in donor must be kept to minimum. This cross sectional study was designed to delineate the causes for deferrals amongst whole blood donors.Methodology: This was a 1 year descriptional study done in a tertiary care teaching hospital Blood Bank in South India. The various causes for deferral of the donor from donation were collected from the donor deferral register which was recorded using the regular questionnaire based interview in the registration card followed by thorough medical history elicitation and examination. The statistical analysis was performed using SPSS version 10.Results: Amongst 30711 donors who attended the blood bank for donation, deferral rate was 9.74%. Out of which there were 2487 (83.11%) temporary and 505 (16.89%) permanent deferrals. The most common cause for deferral was anemia in females whereas among males it was alcohol consumption in the past 12 hours. Conclusion:The deferral rate in this study is comparable to the deferral rates in other centers. The data will be very essential and helpful in testing the applicability of donor selection criteria locally in different geographical settings.

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Quantifying losses to the donated blood supply due to donor deferral and miscollection

Cited by 107 publications

References 23 publications

The Evaluation of Blood Donor Deferral Causes: A Tertiary Care CentrebasedStudy

The Evaluation of Blood Donor Deferral Causes: A Tertiary Care CentrebasedStudy

Pre Donation Deferral a Single Centre Experience

Whole Blood Donor Deferral Causes in a Tertiary Care Teaching Hospital Blood Bank from South India

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