Quantifying public health benefits of PM2.5 reduction and spatial distribution analysis in China

Luo, G.; Zhang, Lanyi; Hu, Xisheng; Qiu, Rongzu

doi:10.1016/j.scitotenv.2020.137445

Cited by 54 publications

(22 citation statements)

References 24 publications

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“…And PM2.5 was one of the important constituents in the haze, plays the most important role in causing adverse health effects. Studies have shown that most respiratory diseases are closely related to atmospheric environmental particulate matter, and atmospheric PM2.5 has a significant effect on the development of respiratory diseases 21 . In the present study, our data showed that PM2.5 exposure induced lung damage, and enhanced the number of inflammatory cells in BALFs and inflammatory cytokines secretion via activating the NLRP3/caspase‐1 pathway.…”

Section: Discussionsupporting

confidence: 62%

PM2.5‐induced pulmonary inflammation via activating of the NLRP3/caspase‐1 signaling pathway

Jia

Liu

Guo

et al. 2020

Environmental Toxicology

106

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Particulate matter 2.5 (PM2.5)‐induced pulmonary inflammation has become a public concern in recent years. In which, the activation of the NLRP3/caspase‐1 pathway was closely related to the inflammatory response of various diseases. However, the promotion effect of the NLRP3/caspase‐1 pathway on PM2.5‐induced pulmonary inflammation remains largely unclear. Here, our data showed that PM2.5 exposure caused lung injury in the mice by which inflammatory cell infiltration occurred in lung and alveolar structure disorder. Meanwhile, the exposure of human bronchial epithelial cells (16HBE) to PM2.5 resulted in suppressed cell viability, as well as elevated cell apoptosis. Moreover, a higher level of inflammatory cytokine and activation of the NLRP3/caspase‐1 pathway in PM2.5‐induced inflammation mice models and 16HBE cells. Mechanistically, pretreatment with MCC950, a NLRP3/caspase‐1 pathway inhibitor, prevented PM2.5‐induced lung injury, inflammatory response, and the number of inflammatory cells in BALFs, as well as promoted cell viability and decreased inflammatory cytokine secretion. Collectively, our findings indicated that the NLRP3/caspase‐1 pathway serves a vital role in the pathological changes of pulmonary inflammation caused by PM2.5 exposure. MCC950 was expected to be the therapeutic target of PM2.5 inhalation mediated inflammatory diseases.

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Section: Discussionsupporting

confidence: 62%

PM2.5‐induced pulmonary inflammation via activating of the NLRP3/caspase‐1 signaling pathway

Jia

Liu

Guo

et al. 2020

Environmental Toxicology

106

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“…Many studies show that air pollutants, in particular particulate matter (PM), contribute to the occurrence or exacerbation of symptoms of many diseases, including upper respiratory tract disease, asthma, chronic obstructive pulmonary disease (COPD), pneumonia, and cardiovascular disease. Fine particles with a particle size of fewer than 10 microns (PM 10 for short) and less than 2.5 microns (PM 2.5 for short) have become two representative pollutants that have a particularly adverse effect on human health [3,4]. PM 10 and PM 2.5 have a significant effect on light scattering and absorption, resulting in reduced visibility in the atmosphere.…”

Section: Introductionmentioning

confidence: 99%

Air Pollution Observations in Selected Locations in Poland during the Lockdown Related to COVID-19

Rogulski

Badyda

2021

Atmosphere

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The coronavirus disease (COVID-19) has caused huge changes in people’s daily habits and had a significant impact on the economy. The lockdowns significantly reduced road traffic and meant that many people worked remotely. Therefore, the question arose as to how the reduced road traffic and stays of residents at home affected the degree of pollution and the structure of major air pollutants. To answer this question, the article presents an analysis of changes in typical air pollutants (PM10, PM2.5, NO2) in the five largest Polish cities and one of the voivodships. The data from the Polish State Environmental Monitoring were used for the analysis. The analysis showed that the period of the first lockdown in Poland (April 2020), despite the reduced road traffic, resulted in a significant increase in PM10 emissions (9–91% during working days and an average of 30% on Saturdays and Sundays), a slight increase in PM2.5 emissions (on average from 2% to 11% for all analyzed locations), and a reduction in NO2 emissions (on average from 6% to 11% for all analyzed locations) compared to the period before the lockdown. However, the changes were not homogeneous—in Łódź and Warsaw, in most cases, an increase in all analyzed pollutants was observed, and the greatest decrease in pollution took place in Małopolska voivodship (including Kraków). Comparing the data from April 2020 to the data from April 2019, the overall difference in the PMs concentrations was small, although there are places where there has been a significant decrease (Wrocław, Poznań), and there were also places where the concentration increased (Warsaw, Łódź, Małopolska). In the case of nitrogen dioxide, pollution concentration decreased in most locations. The only exception was the background stations in Warsaw, where the increase was 27%.

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“…posing adverse effect on human health (Luo et al 2020, Wang et al 2020a. PM10 and PM2.5 have significant scattering and absorption effects on light, resulting in reduced atmospheric visibility.…”

Section: Accepted Articlementioning

confidence: 99%

Observations on the particle pollution of the cities in China in the Coronavirus 2019 closure: Characteristics and lessons for environmental management

Yao

Niu

Zhang

et al. 2021

Integr Envir Assess & Manag

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Particulate matter in the air seriously affects human health and has been a hot topic being discussed. Because of the COVID-19 lockdown of the cities in China, sources of This article is protected by copyright. All rights reserved. Accepted Article the particulate matter including gasoline burning vehicles, dust producing building sites, coal-fired factories, almost all stopped working since the end of January 2020. It was not until early April that outdoor activities recovered. Ten cities were selected as the observation sites in the period from 12/19/2019 to 04/30/2020, covering the periods of the pre-closure, the closure and the gradual resumption. 11720 groups of data were obtained and four indicators were applied to assess the characteristics of the particle pollution in the period. The quality of the atmospheric environment was visually influenced by human activities in the four months. The PM10 concentrations decreased slightly in February and March, and then began to increase gradually after April with the gradual recovery of production. The concentrations of PM2.5 reduced greatly in most regions especially in northern cities, during the closure and maintained a relatively stable level in the following three months. The trends of PM10 and PM2.5 indicated that the reduced human activities during the COVID-19 lockdown made the concentrations of the particulate matter in the air decreased, and the difference between the PM10 and PM2.5 trends might be due to the different sources of the two particles and their different aerodynamics. However, during the closure, the pollution of the particulate matter in the cities still remained at a high level, which indicated that some ignored factors except the outdoor production activities, automobile exhaust and sites' dust might have been contributing much to the PM10 and PM2.5 concentrations, and the traceability of the particulate matter should be paid further attention in environmental management.

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Quantifying public health benefits of PM2.5 reduction and spatial distribution analysis in China

Cited by 54 publications

References 24 publications

PM2.5‐induced pulmonary inflammation via activating of the NLRP3/caspase‐1 signaling pathway

PM2.5‐induced pulmonary inflammation via activating of the NLRP3/caspase‐1 signaling pathway

Air Pollution Observations in Selected Locations in Poland during the Lockdown Related to COVID-19

Observations on the particle pollution of the cities in China in the Coronavirus 2019 closure: Characteristics and lessons for environmental management

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