2016
DOI: 10.1001/jama.2016.3427
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Quantifying the Benefits and Risks of Methylphenidate as Treatment for Childhood Attention-Deficit/Hyperactivity Disorder

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Cited by 12 publications
(15 citation statements)
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“…25 Adult functioning after childhood ADHD is generally worse when symptoms persist into adulthood. 26 Better designed randomised controlled trials that minimise bias are warranted to confirm the clinical effectiveness of stimulant use in adults.…”
Section: Adultsmentioning
confidence: 99%
“…25 Adult functioning after childhood ADHD is generally worse when symptoms persist into adulthood. 26 Better designed randomised controlled trials that minimise bias are warranted to confirm the clinical effectiveness of stimulant use in adults.…”
Section: Adultsmentioning
confidence: 99%
“…In fact, several more recent studies have found that medication treatment is associated with decreased substance-related risk (1820). At present, uncertainty remains regarding the extent to which medication treatment impacts substance-related problems (2124). …”
Section: Introductionmentioning
confidence: 99%
“…Conclusions from randomized clinical trials have been constrained by sample sizes and treatment durations that may be insufficient to detect rare-yet-serious substance-related events, questions regarding generalizability, and ethical concerns about withholding efficacious treatments (24, 25). At the same time, conclusions from observational studies have been constrained by the possibility of confounding from differences between patients who are and are not treated pharmacologically (i.e., confounding by indication) (16).…”
Section: Introductionmentioning
confidence: 99%
“…Thus, reviews have concluded that there is not sufficient evidence to judge whether there is shortand long-term harm of ADHD medication for seizures and other rare events. [14][15][16][17][18][19] The aim of the current study was to examine concurrent and long-term associations between ADHD medication use and seizures using a large national database of commercial health insurance claims. The sample enabled us to estimate the magnitude of the association among patients with and without a seizure history with precision.…”
mentioning
confidence: 99%