Quantifying the magnitude of local tendon injury from electrosurgical transection

Dandu, Navya; Nelson, Brad B.; Easley, Jeremiah T.; Huddleston, Hailey P.; DeFroda, Steven F.; Bisazza, Katie T.; Garrigues, Grant E.; Yanke, Adam B.

doi:10.1016/j.jse.2021.08.020

Cited by 1 publication

(1 citation statement)

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“…Hemostasis during surgery is commonly accomplished using monoand bipolar electrocautery devices that generate intense heat to cauterize blood vessels. Unfortunately, the use of these devices is necessary but can impair healing, cause skin damage, produce charring, and result in tissue scarring [1]. In contrast, cold plasma technology has been explored as an alternative way to control bleeding through platelet activation and blood coagulation [2,3] without intense heating or extensive tissue damage.…”

Section: Introductionmentioning

confidence: 99%

Evaluating the Healing Potential of J-Plasma Scalpel-Created Surgical Incisions in Porcine and Rat Models

Elmore,

Minissale,

Israel

et al. 2024

Biomedicines

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Cold atmospheric plasma devices generate reactive oxygen and nitrogen species that can be anti-microbial but also promote cell migration, differentiation, and tissue wound healing. This report investigates the healing of surgical incisions created using cold plasma generated by the J-Plasma scalpel (Precise Open handpiece, Apyx Medical, Inc.) compared to a steel scalpel in in vivo porcine and rat models. The J-Plasma scalpel is currently FDA approved for the delivery of helium plasma to cut, coagulate, and ablate soft tissue during surgical procedures. To our knowledge, this device has not been studied in creating surgical incisions but only during deeper dissection and hemostasis. External macroscopic and histologic grading by blinded reviewers revealed no significant difference in wound healing appearance or physiology in incisions created using the plasma scalpel as compared with a steel blade scalpel. Incisions created with the plasma scalpel also had superior hemostasis and a reduction in tissue and blood carryover. Scanning electron microscopy (SEM) and histology showed collagen fibril fusion occurred as the plasma scalpel incised through the tissue, contributing to a sealing effect. In addition, when bacteria were injected into the dermis before incision, the plasma scalpel disrupted the bacterial membrane as visualized in SEM images. External macroscopic and histologic grading by blinded reviewers revealed no significant difference in wound healing appearance or physiology. Based on these results, we propose additional studies to clinically evaluate the use of cold plasma in applications requiring hemostasis or when an increased likelihood of subdermal pathogen leakage could cause surgical site infection (i.e., sites with increased hair follicles).

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Section: Introductionmentioning

confidence: 99%