Quantitative analysis of anterior segment optical coherence tomography images: the Zhongshan Angle Assessment Program

Console, James W; Sakata, Lisandro M.; Aung, Tin; Friedman, David S.; He, Mingguang

doi:10.1136/bjo.2007.129932

Cited by 157 publications

(131 citation statements)

References 12 publications

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“…21 The only observer input needed was to determine the location of the two scleral spurs, which was done by a glaucoma specialist (SM). Because localization of the scleral spur was very important to obtain accurate measurements, images in which the scleral spurs were not clearly visible were eliminated.…”

Section: Methodsmentioning

confidence: 99%

Lens parameters as predictors of intraocular pressure changes after phacoemulsification

Moghimi

Abdi

Latifi

et al. 2015

Eye

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Purpose To evaluate intraocular pressure (IOP) change after cataract surgery in nonglaucomatous eyes with narrow and open angles (OAs) and its relation to novel lens parameters measured by anterior segment optical coherence tomography (AS-OCT). Setting University affiliated hospital, Farabi Eye Hospital, Tehran, Iran. Design Prospective interventional case series. Methods In this prospective study, 85 nonglaucomatous eyes underwent phacoemulsification and lens implantation. Thirty-nine eyes had OAs and 46 eyes had narrow angles (NAs). IOP and biometric parameters were measured by AS-OCT preoperatively and 3 months after surgery. Change in IOP and its relation to biometric parameters, including lens vault (LV), anterior vault (AV), defined as the sum of the LV and the ACD, and relative LV (rLV), defined as the ratio of the LV to the AV, were evaluated. The main outcome measure was degree of IOP change after phacoemulsification. Results Of the 85 patients included in the analysis, 35 were male and 50 were female with an overall mean age of 62.2 ± 8.9 years. The average IOP reduction was − 4.95 ± 2.26 mm Hg, from a preoperative mean of 17.12 ± 2.47 mm Hg, at 3 months after cataract surgery. The amount of IOP reduction was significantly greater in the NA compared with the OA group. In multivariate linear regression analysis, preoperative IOP and AV were significantly associated with IOP decrease (all ≤ 0.03). Conclusion Cataract surgery results in IOP reduction in both OA and NA eyes. The amount of IOP reduction is related to AV.

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Section: Methodsmentioning

confidence: 99%

Lens parameters as predictors of intraocular pressure changes after phacoemulsification

Moghimi

Abdi

Latifi

et al. 2015

Eye

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“…The repeatability of the measured values in images obtained by the same operator and between different operators was not assessed, although this has been performed in other studies. 11,19 To avoid corneal lesions that could interfere with the quality of images obtained with AS-OCT, gonioscopy was always performed after AS-OCT imaging. It is possible that this sequence of examinations may have influenced our results.…”

Section: Gonioscopymentioning

confidence: 99%

Comparison of Visante and slit-lamp anterior segment optical coherence tomography in imaging the anterior chamber angle

Sakata

Wong

et al. 2009

Eye

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“…Determination of angle parameters using semiautomated software leads to variability in measurements and this is largely due to the need of manual identification of the sclera spur [96]. Using Visante OCT the scleral spur individuation is possible in approximately 70% of anterior segment images [97]. Rates of detection are worse in the superior and inferior quadrants because of the eyelids.…”

Section: Anterior Segment Optical Coherence Tomography (As-oct)mentioning

confidence: 99%

Angle Closure Glaucoma: Pathogenesis and Evaluation. A Review

Fea¹,

Bertaina²,

Consol³

et al. 2012

J Clinic Experiment Ophthalmol

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Pupillary block is the most common mechanism responsible for angle closure [9], but the anatomical configuration which causes a plateau iris may be a more common mechanism than was previously thought. Pupillary block mechanismIn pupillary block, the resistance to aqueous flow from the posterior to anterior chamber is at the level of the pupil, creating a pressure gradient that causes forward bowing of the peripheral iris and closure of the angle [10,11].Aqueous humor flow from the posterior chamber into the anterior chamber is regulated by a differential pressure between the anterior and the posterior chamber. This pressure differential may increase greatly when the dimensions of the iris-lens channels are changed. As this pressure increment increases, the iris becomes more convex and can close angle.Extreme anterior iris-bulging, iris bombé would be expected with pressure differentials of 10-15 mm Hg [12]. The variables that influence the flow through the ''pinch region'' (iris-lens channels) and influence the pressure differential and related iris contour have been studied extensively [12][13][14][15][16].Changes in pupillary size, increased channel length and decreased height, movement of the iris insertion posteriorly or of the lens anteriorly, were associated with an expected increase in the pressure differential. Other variables exist and interact to determine the iris contour, including eye size, especially the dimensions of the anterior segment, lens size and position, iris stroma and iris musculature characteristics, ciliary body anatomy, and physiologic parameters including aqueous humor flow rate, facility of outflow, vitreousaqueous fluid flow, and the effects of accommodation and blinking [9]. AbstractPrimary open angle glaucoma (PACG) is a major cause of blindness especially in Asia. The pathogenesis of this condition has been widely investigated. Traditionally gonioscopy is the method of choice for the esamination of patients considered to be at risk for angle closure, but it is a rather invasive procedure and it is reported to be primarily used by glaucoma specialists. Recently newer ultrasound and optical methods for the evaluation of the anterior chamber angle have been introduced in the clinical practice, with distinct advantages and disadvantages both compared to each other and to gonioscopy. This review will address the pathogenesis of PACG, the use of gonioscopy and will evaluate the newer methods of angle examination.

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Quantitative analysis of anterior segment optical coherence tomography images: the Zhongshan Angle Assessment Program

Cited by 157 publications

References 12 publications

Lens parameters as predictors of intraocular pressure changes after phacoemulsification

Lens parameters as predictors of intraocular pressure changes after phacoemulsification

Comparison of Visante and slit-lamp anterior segment optical coherence tomography in imaging the anterior chamber angle

Angle Closure Glaucoma: Pathogenesis and Evaluation. A Review

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