Quantitative Analysis of Bisphenol A Leached from Household Plastics by Solid–Phase Microextraction and Gas Chromatography–Mass Spectrometry (SPME–GC–MS)

Abstract

The measurement of trace levels of bisphenol A (BPA) leached out of household plastics using solid-phase microextraction (SPME) with gas chromatography−mass spectrometry (GC−MS) is reported here. BPA is an endocrine-disrupting compound used in the industrial manufacture of polycarbonate plastic bottles and epoxy resin can liners. This experiment allows students to use modern instrumentation and analytical techniques to investigate a timely and relevant issue involving the contamination of food products by a packaging component. The impact of handling conditions and container type on the quantity of BPA released from the plastics is explored. This experiment is suitable for an undergraduate analytical chemistry or instrumental analysis course and requires two, 3-h laboratory periods to complete.

International Trade Regulations on BPA: Global Health and Economic Implications

“…Especially, it mimics estrogen. Moreover, BPA can arouse many additional health problems, including weight gain, early-onset of puberty, infertility, behavioral changes, cardiovascular effects and diabetes (Morgan et al, 2011;Johnson et al, 2012;Wang et al, 2012).…”

Core‐shell Hierarchical Enzymatic Biosensor Based on Hyaluronic Acid Capped Copper Ferrite Nanoparticles for Determination of Endocrine‐disrupting Bisphenol A

“…Therefore, it is important to develop sensor platforms for determination of BPA with high sensitivity, selectivity, wide dynamic working range and a low detection limit. Although chromatographic methods such as high‐pressure liquid chromatography (HPLC) [3], gas chromatography‐mass spectrometry (GC‐MS) [4] are traditionally used to detect bisphenol A. These techniques have disadvantages such as requiring pre‐treatment procedures with expert analyst, high cost and not being able to perform analysis on‐site [5].…”

An Integrated Database of Common Chemicals and Chemistry Demonstrations and Student Experiments Used in Hungary

“…This challenge prompted many educators to approach this problem from a pragmatic point of view by using chemicals, equipment, and devices that are available or can be simply transformed from everyday, frequently household materials and tools. The large number of publications on this topic include inter alia analytical, − electrochemical, − synthetic, − and isolation experiments.…”