Quantitative analysis of brain synaptophysin (p38) in offspring of male rats with chronic morphine intoxication

Abstract

Cerebral synapses in offspring of male rats treated with morphine for a month before mating were studied using synaptophysin (p38) as a synaptic marker. The content of p38 in the nucleus accumbens, hippocampus, and layers III and V of the somatosensory cortex was below the control, while no significant changes were found in the motor cortex, caudate nucleus, and ventrolateral thalamic nuclei.