Quantitative analysis of contrast-enhanced ultrasound combined with ultrasound in the unifocal papillary thyroid micro-carcinoma

Zhang, Xiaohui; Zhang, Min; Jin, Linyuan; Tang, Xianpeng; Hu, Qiang; Cheng, Guangming; Xiao, Yaocheng

doi:10.1016/j.medengphy.2022.103840

Cited by 1 publication

(1 citation statement)

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“…Therefore, when this manifestation occurs, it is necessary to consider the possibility of malignancy. Recent studies [29] found that the proportion (46.15%) of malignant nodules R-AS > 1 (the ratio of nodule's ascending slope to surrounding normal thyroid tissue's ascending slope) was signi cantly higher than that of benign nodules (12.86%) (p < 0.001), indicating that the ascending slope of malignant nodules was signi cantly higher than that of benign nodules, which is not consistent with our results. Although the mean value of sharpness in malignant nodules is higher than in benign nodules, the difference is insigni cant (p = 0.180).…”

Section: Discussioncontrasting

confidence: 99%

Diagnostic value of qualitative and quantitative parameters of contrast-enhanced ultrasound for differentiating thyroid carcinoma nodules from benign thyroid nodules

Fan

Zhou

Tao

et al. 2023

Preprint

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Objective To explore the diagnostic value of qualitative and quantitative parameters of contrast-enhanced ultrasound (CEUS) for differentiating thyroid carcinoma nodules and benign thyroid nodules. Method The qualitative and quantitative CEUS parameters of 290 thyroid nodules confirmed by pathology were analyzed retrospectively. The evaluation indexes included wash in, wash out, enhancement degree, enhancement homogeneity, morphology after angiography, and ring enhancement. Results Malignant nodules had an unclear margin, uneven perfusion, and low perfusion (all p < 0.05). The internal peak of malignant nodules was lower than that of benign nodules, the TP at the outer edge of malignant nodules was higher than that of benign nodules, the sharpness at the outer edge of malignant nodules was lower than that of benign nodules, and the AUC at the outer edge of malignant nodules was lower than that of benign nodules (all p < 0.05). Multivariate analysis showed that internal peak and external sharpness were independent risk factors for the diagnosis of differentiated thyroid carcinoma and benign thyroid nodules. Conclusion The qualitative and quantitative analysis of CEUS can provide valuable information for the differential diagnosis of differentiated thyroid carcinoma (DTC) and benign thyroid nodules.

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Section: Discussioncontrasting

confidence: 99%