Quantitative analysis of morphological and functional alterations of the meibomian glands in eyes with marginal entropion

Yang, Moon Sik; Sa, Ho-Seok; Kim, Nam-Ju; Jeon, Hyun Sun; Hyon, Joon Young; Choung, Ho Kyung; Khwarg, Sang In

doi:10.1371/journal.pone.0267118

Cited by 4 publications

(2 citation statements)

References 29 publications

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“…Yang et al [15] reported no significant differences in the drop-out rate of meibomian glands, according to preoperative measurements in the follow-up performed up to the fifth month in patients who were operated on for marginal entropion. The reason why this difference was not detected can be explained by the abnormal positioning of the orifices of the meibomian glands in the eyelids of patients with marginal entropion.…”

Section: Discussionmentioning

confidence: 97%

Evaluation of the effect of eyelid disorder surgeries on tears and anterior segment parameters with meibography and corneal topography

Eroğul¹,

Gülal²

2022

J Surg Med

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Background/Aim: Abnormalities of eyelid shape, including ptosis, entropion, ectropion, lagophthalmos, and dermatochalasis, can occur at any age and affects the patient’s life quality, visual functions, and comfort. These abnormalities can be regarded as illnesses and can be cured medically and surgically. Meibomian glands are large sebaceous glands located in the lower and upper eyelids. Our study aimed to observe changes in anterior cornea segment parameters and meibomian glands of patients undergoing surgery for eyelid shape abnormalities. Methods: Our sample comprised 31 patients, who were operated on at Afyonkarahisar Health Sciences University Hospital, were examined with respect to cornea topographic measurements and the drop-out of meibomian glands at the pre-operative and first-month post-operative processes and post-operative third month. In this prospective cohort method study, the surgical eyes of the patients were determined as the study group and the healthy eyes as the control group. Results: Surgical and healthy eyes of 31 patients were included in this study (N=62). The sample comprised 18 male and 13 female patients. The average age and standard deviation values of patients were determined as 66.50 (17.315) in males and 65.92 (13.714) (P = 0.659) in females. In terms of anterior cornea segment parameters (K1, K2, ACA, ACD, ACV, and CCT), no prominent differences were found in pre-operative and post-operative results (K1, K2, ACA, ACD, ACV, and CCT) in both the study and control groups. Meibography revealed that the increased meibomian gland drop-out of surgical eye measurements of pre- and post-operative was statistically significant (P < 0.001), whereas the change seen in healthy eyes was not statistically significant (P = 0.051). Furthermore, although the change through meibomian glands of entropion patients was not significant (P = 0.066), the drop-out of the meibomian gland of the other surgery cases (ptosis, ectropion, lagophthalmos, blepharoplasty, and dermatochalasis surgery) was found to be statistically significant (P = 0.038). Conclusion: Surgeries to correct abnormalities in eyelid shape can lead patients to meibomian gland drop-out. Pre-operative assessment of patients whose surgeries are planned, and post-operative monitoring, must be done meticulously in order to minimize the likelihood of symptoms and avoid meibomian gland dysfunction.

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Section: Discussionmentioning

confidence: 97%

Evaluation of the effect of eyelid disorder surgeries on tears and anterior segment parameters with meibography and corneal topography

Eroğul¹,

Gülal²

2022

J Surg Med

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“…Likewise, entropion can lead to ocular surface irritation and, eventually, OSD. Patients with entropion should be evaluated carefully for meibomian gland dysfunction and OSD [36]. Figure 3 shows an anterior segment photograph of a patient with entropion and inferior corneal pannus.…”

Section: Preoperative Preventive Measures Postoperative Assessment An...mentioning

confidence: 99%

A review of oculoplastic surgery and ocular surface disorders

Ciftci¹,

Selver²

2022

Med Hypothesis Discov Innov Optom

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Background: Ocular surface health is closely related to the condition of the ocular adnexa, particularly the eyelids. Both ocular adnexal disorders and oculoplastic procedures performed to treat them can cause ocular surface disorders (OSD). In this review, we aimed to summarize the relationship between oculoplastic procedures and OSD. Methods: In this narrative review, an electronic search of the PubMed/MEDLINE database was conducted using various combinations of keywords including “oculoplastic surgery,” “ocular surface disorders,” “dry eye,” and “management,” without time or language limitations, to include studies concerning oculoplastic surgery and OSD. Results: We included articles involving oculoplastic procedures and OSD with discussions of preventive approaches and management strategies in this context. For a systematic approach, the preoperative assessments and postoperative treatment of patients were retrieved and summarized. Preoperative preventive measures included evaluation of tear film break-up time, tear osmolarity, tear meniscus area and height measurement by anterior segment optic coherence tomography, lipid layer thickness by interferometer, corneal staining and Oxford Scheme, Schirmer test, blink rate and completeness, ocular surface disease index scoring, eyelid closure, and Bell’s phenomenon. Postoperative assessments included the presence and severity of dry eye and early management of dry eye with artificial tears, topical anti-inflammatory medications, and night taping; evaluation of the presence of chemosis, and, if present, management with pharmacologic, mechanical, or surgical therapies when needed; and prompt detection and treatment of lagophthalmos and consequent exposure keratopathy. Conclusions: Careful preoperative examination of the ocular surface is mandatory to reduce or eliminate complications after oculoplastic surgery. Ocular surface-related complications that surgeons encounter after oculoplastic surgery should be promptly diagnosed and treated.

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Evaluation of visual field and ocular surface parameters by clinical comparison after blepharoplasty for dermatochalasis

Ulas,

Ozcan,

Yar

et al. 2024

Journal Français d'Ophtalmologie

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Quantitative analysis of morphological and functional alterations of the meibomian glands in eyes with marginal entropion

Cited by 4 publications

References 29 publications

Evaluation of the effect of eyelid disorder surgeries on tears and anterior segment parameters with meibography and corneal topography

Evaluation of the effect of eyelid disorder surgeries on tears and anterior segment parameters with meibography and corneal topography

A review of oculoplastic surgery and ocular surface disorders

Evaluation of visual field and ocular surface parameters by clinical comparison after blepharoplasty for dermatochalasis

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