Quantitative Assessment of Dry Eye Parameters After Müller’s Muscle-Conjunctival Resection

Bautista, Sana; Wladis, Edward J.; Schultze, R.

doi:10.1097/iop.0000000000001103

Cited by 13 publications

(4 citation statements)

References 8 publications

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“…Additionally, Dailey et al 26 determined that conjunctivo-mullerectomy did not affect tear production. Another study ascertained no changes in the ocular surface disease parameters of tear breakup time, lipid layer thickness, and osmolarity after this surgery 27 . Our results agree with these prior ndings in that we found punctate epithelial erosion in 40 eyes (15.5%) without signi cant symptoms or the need for treatment.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Clinical Outcomes of Conjunctivo-Mullerectomy for Varying Degrees of Ptosis

Pornpanich,

Shanokprasith,

Jaru-ampornpan

et al. 2023

Preprint

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To compare the success of conjunctivo-mullerectomy in patients with varying degrees of ptosis and identify factors affecting outcomes and complications. The Prospective cohort was studied in patients with ptosis undergoing conjunctivo-mullerectomy with or without tarsectomy were enrolled. Ptosis was classified as mild, moderate, and severe per margin-to-reflex distance 1 (MRD1). Postoperative MRD1, complications, and 3-month success rates were evaluated.The study enrolled 258 ptotic eyes of 159 patients. Most eyes (233; 90.3%) achieved surgical success, 14 (5.4%) were overcorrected, and 11 (4.3%) were undercorrected. The success rates for mild, moderate, and severe ptosis were 96.6%, 91.7%, and 83.5%, respectively. The mild and moderate ptosis groups had a nonsignificant difference in success (-4.9%; 95% CI, -12.0–4.5%; P = 0.36). However, the mild and severe ptosis groups’ rates significantly differed (-13.1%; 95% CI, -23.6% to -1.9%; P = 0.03). For all 3 ptosis groups, the success rates of individuals undergoing surgery without tarsectomy did not significantly differ. Patients undergoing conjunctivo-mullerectomy with tarsectomy had an increased risk of unsuccessful surgery (OR 3.103; 95% CI, 1.205–7.986; P = 0.019). In conclusions, Conjunctivo-mullerectomy is safe and effective for all ptosis severities. The success rate was significantly lower for severe ptosis than mild or moderate ptosis. Levator muscle function was not associated with unsuccessful outcomes, but tarsectomy was.

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Section: Discussionmentioning

confidence: 99%

Comparison of Clinical Outcomes of Conjunctivo-Mullerectomy for Varying Degrees of Ptosis

Pornpanich,

Shanokprasith,

Jaru-ampornpan

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…Additionally, Dailey et al 28 determined that conjunctivo-mullerectomy did not affect tear production. Another study ascertained no changes in the ocular surface disease parameters of tear break-up time, lipid layer thickness, and osmolarity after this surgery 29 . Our results agree with these prior findings in that we found punctate epithelial erosion in 40 eyes (15.5%) without significant symptoms or the need for treatment.…”

Section: Discussionmentioning

confidence: 99%

Comparison of clinical outcomes of conjunctivo-mullerectomy for varying degrees of ptosis

Pornpanich,

Shanokprasith,

Jaru-ampornpan

et al. 2023

Sci Rep

View full text Add to dashboard Cite

To compare the success of conjunctivo-mullerectomy in patients with varying degrees of ptosis and identify factors affecting outcomes and complications. The prospective cohort was studied in patients with ptosis undergoing conjunctivo-mullerectomy with or without tarsectomy were enrolled. Ptosis was classified as mild, moderate, and severe per margin-to-reflex distance 1 (MRD1). Postoperative MRD1, complications, and 3-month success rates were evaluated. The study enrolled 258 ptotic eyes of 159 patients. Most eyes (233; 90.3%) achieved surgical success, 14 (5.4%) were overcorrected, and 11 (4.3%) were undercorrected. The success rates for mild, moderate, and severe ptosis were 96.6%, 91.7%, and 83.5%, respectively. The mild and moderate ptosis groups had a nonsignificant difference in success (− 4.9%; 95% CI − 12.0% to 4.5%; P = 0.36). However, the mild and severe ptosis groups’ rates significantly differed (− 13.1%; 95% CI − 23.6% to − 1.9%; P = 0.03). For all 3 ptosis groups, the success rates of individuals undergoing surgery without tarsectomy did not significantly differ. Patients undergoing conjunctivo-mullerectomy with tarsectomy had an increased risk of unsuccessful surgery (OR 3.103; 95% CI 1.205–7.986; P = 0.019). In conclusions, Conjunctivo-mullerectomy is safe and effective for all ptosis severities. The success rate was significantly lower for severe ptosis than mild or moderate ptosis. Levator muscle function was not associated with unsuccessful outcomes, but tarsectomy was.

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“…The Fasanella-Servat procedure includes the addition of a superior tarsectomy with the typical Muller muscle conjunctival resection 38. Dry eye disease can be an unwanted side effect of a transconjunctival approach due to transection of the goblet cells and accessory lacrimal glands, but studies have shown that tear break up times in postoperative patients are similar following surgery 75,77. Corneal abrasions should also be closely monitored with the addition of a superior tarsectomy.…”

Section: Acquired Causesmentioning

confidence: 99%

Pediatric Ptosis: A Review of Less Common Causes

Jones¹,

Ma²,

Yang³

et al. 2021

International Ophthalmology Clinics

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Quantitative Assessment of Dry Eye Parameters After Müller’s Muscle-Conjunctival Resection

Abstract: MMCR does not appear to change clinically meaningful ocular surface disease parameters, and postoperative dryness did not result from this procedure. In appropriately selected patients, MMCR can be safely performed without increased concerns regarding postoperative dry eye disease.

Cited by 13 publications

References 8 publications

Comparison of Clinical Outcomes of Conjunctivo-Mullerectomy for Varying Degrees of Ptosis

Comparison of Clinical Outcomes of Conjunctivo-Mullerectomy for Varying Degrees of Ptosis

Comparison of clinical outcomes of conjunctivo-mullerectomy for varying degrees of ptosis

Pediatric Ptosis: A Review of Less Common Causes

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