Quantitative Assessment of the Quality of Treatment Planning for Patients with Advanced Cervical Cancer

Lebedenko, I. M.; Романова, Е. А.; Белова, А. А.; Кравец, О. А.; Mezheumova, A. A.

doi:10.1007/s10527-018-9826-8

Cited by 5 publications

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“…Various authors have discussed the HI for gynecological cancer (Kataria et al, 2012;Lebedenko et al, 2018;Atiq et al, 2019), which gives a clear picture about the dose uniformity within the tumour. Hot and cold spots that affect the radiation outcome can be easily identified using this index.…”

Section: Discussionmentioning

confidence: 99%

IMRT as an Alternative Technique for Intracavitary Brachytherapy in Patients with Carcinoma of the Cervix: A Feasibility Study Using Unified Dosimetric Index

Balan,

Ramasubramanian

2023

Asian Pac J Cancer Prev

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Objective: Intracavitary brachytherapy (ICBT) plays an important role in the management of carcinoma of the cervix. This study attempts to find the feasibility of intensity-modulated radiation therapy (IMRT) as a boost for patients who are not suitable for ICBT in order to improve their disease-free and overall survival. Methods: Twenty patients with carcinoma of the cervix were included in this study. Nine fields of IMRT and ICBT plans were generated for PTV Boost . Various dosimetric indices like coverage, conformity, homogeneity, and gradient index were calculated, and the corresponding unified dosimetric index (UDI) values were generated. Plans were classified based on combined UDI, and the UDI values were compared with those of ICBT. In addition, rectum and bladder doses were compared. Results: All the dosimetric indices were within acceptable limits except for the gradient index. The gradient index of the IMRT and ICBT plans were 8.77 ± 0.26 and 1.33 ± 0.06 respectively (p < 0.0001). The mean of combined UDI with standard deviation was 32.557 ± 8.940 and plan quality was calculated from these values. Rectum and bladder doses for ICBT were lesser than IMRT (p < 0.0001). Conclusion: ICBT is the gold standard for boost RT in carcinoma of the cervix patients. IMRT boost is feasible for patients who are unsuitable on medical grounds for brachytherapy.

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Section: Discussionmentioning

confidence: 99%

IMRT as an Alternative Technique for Intracavitary Brachytherapy in Patients with Carcinoma of the Cervix: A Feasibility Study Using Unified Dosimetric Index

Balan,

Ramasubramanian

2023

Asian Pac J Cancer Prev

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“…В соответствии с международными рекомендациями для технологий 3D-CRT, IMRT и RapidArc, HI рассчитывали по кумулятивной ГДО. Это отношение разницы дозы D 2 % около максимума, охватывающей 2 % мишени или критического органа, и минимального значения дозы, охватывающей 98 % объема мишени или критического органа D 98 %, к нормирующему значению D 50 % [4][5][6]. В идеальном случае, при HI = 0, дозовое распределение полностью однородное.…”

Section: индекс гомогенности дозы Hiunclassified

Quantitative Assessment of Distance Radiotherapy Plans for Patients with Uterine Cancer

Lebedenko¹,

Usmanova²,

Mezheumova

2022

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Purpose: To carry out a quantitative assessment of the quality of planning the remote radiotherapy component of patients with uterine body cancer for three different radiotherapy technologies: 3D conformal radiation therapy 3D-CRT, radiation therapy with intensity modulation IMRT, and with intensity modulation in the rotational mode RapidArc. To determine radiation exposure to critical organs.Material and methods: Radiotherapy plans for 102 patients were calculated using the Eclipse (Varian) planning system. Plans were evaluated using homogeneity and conformity indices from dose-volume histograms. When analyzing dose loads on the rectum, bladder and pelvic bones, a differential dose-volume characteristic was used, which reflects the modal dose D dif . Radiotherapy was carried out on accelerators of the ClinaciX (Varian) model with a photon of 6 MV.Results and conclusion: It turned out that 3D-CRT and IMRT are the most favorable methods for the remote component of radiotherapy. The smallest value of the modal dose D dif for the rectum is achieved with the RapidArc method and is 41 ± 10 Gy. The smallest value of the modal dose D dif for the bladder is also achieved with the RapidArc method and is 45 ± 9 Gy. The dose loads on the femoral heads are approximately the same for all three irradiation methods.

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Quantitative Assessment of the Quality of Remote Irradiation Planning for Cancer Patients

et al. 2022

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Quantitative Assessment of the Quality of Treatment Planning for Patients with Advanced Cervical Cancer

Cited by 5 publications

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IMRT as an Alternative Technique for Intracavitary Brachytherapy in Patients with Carcinoma of the Cervix: A Feasibility Study Using Unified Dosimetric Index

IMRT as an Alternative Technique for Intracavitary Brachytherapy in Patients with Carcinoma of the Cervix: A Feasibility Study Using Unified Dosimetric Index

Quantitative Assessment of Distance Radiotherapy Plans for Patients with Uterine Cancer

Quantitative Assessment of the Quality of Remote Irradiation Planning for Cancer Patients

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