Quantitative Automated Assessment of Myocardial Perfusion at Cardiac Catheterization

Boyle, Andrew; Schuleri, Karl H.; Liénard, Jean‐Sylvain; Vaillant, Régis; Chan, Michael; Zimmet, Jeffrey; Mazhari, Ramesh; Centola, Marco; Feigenbaum, Gary S.; Dib, Joud; Kapur, Navin K.; Hare, Joshua M.; Resar, Jon R.

doi:10.1016/j.amjcard.2008.05.064

Cited by 8 publications

(2 citation statements)

References 8 publications

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“…For a limitation of our technique, the impairment of local perfusion cannot be assessed quantitatively. A quantitative assessment of coronary DSA has been tried in several reports [10,11]. Further development of the analytical method is needed.…”

Section: Discussionmentioning

confidence: 99%

Coronary artery tree and myocardial perfusion in patients with tako-tsubo cardiomyopathy: Evaluation with coronary digital subtraction angiography

Nagayoshi

Nakaura

Awai

et al. 2011

Journal of Cardiology Cases

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Tako-tsubo cardiomyopathy is characterized by transient left ventricular contractile dysfunction. The precise etiology of tako-tsubo cardiomyopathy remains to be elucidated. We performed coronary angiography in two patients with tako-tsubo cardiomyopathy and evaluated the coronary microcirculation by digital subtraction angiography (DSA). In the acute phase of tako-tsubo cardiomyopathy, coronary DSA demonstrated severely reduced perfusion in the apex. Follow-up DSA showed the restoration of normal myocardial perfusion in the apex. Coronary DSA can simultaneously depict the coronary vessels and myocardial perfusion abnormalities. Furthermore, DSA can also show the relationship between the perfusion territory of the coronary arteries and the region of impaired myocardial perfusion. This technique might support the central role of microcirculation disturbance in tako-tsubo cardiomyopathy.

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Section: Discussionmentioning

confidence: 99%

Coronary artery tree and myocardial perfusion in patients with tako-tsubo cardiomyopathy: Evaluation with coronary digital subtraction angiography

Nagayoshi

Nakaura

Awai

et al. 2011

Journal of Cardiology Cases

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“…As image processing for myocardial perfusion imaging [6], [7], [9], firstly, ECG (electrocardiogram) gated background image subtraction is applied to synchronize the perfusion images at a given cardiac phase, and also to enhance contrast agent pixels of the perfusion regions. Secondly, image pixel or ROI (region-of-interest) measurements are implemented on the 978-1-4673-2030-6/12/$3l.00 ©20 12 IEEE subtraction images, yielding TDC (time-density-curve) of temporal distribution of contrast agent.…”

Section: Methodsmentioning

confidence: 99%

Linear quantification correction for myocardial perfusion imaging from x-ray coronary angiography

Yao

Sakaguchi

Yousuf

et al. 2012

2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)

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Myocardial perfusion imaging from x-ray coronary angiography is important with clinical bene fi ts because online real-time assessment of myocardial blood flow can promote the clinical outcomes of interventional treatments for coronary artery disease. In this paper, we aim at the nonlinearity problem of contrast image measurements for the perfusion estimation, since x-ray nonlinear responses of iodinated contrast agent is always an important concern when lacking of x-ray depth information on 2D angiography. A new approach is developed to perform linear quantification correction to angiographic measurements in terms of iodine concentration for estimated body thickness. We recognize the causes of nonlinear measurements from three different sources, that is, image processing artifacts of background subtraction, x-ray physics causes of beam hardening, photon scattering and detector glare if image intensifier applied, as well as clinical application issue of residual contrast agents in myocardium during cardiac catheterization heart procedure. Correspondingly, the developed approach involves three countermeasures to handle the three nonlinear sources. In order to compensate the registration artifacts of background subtraction, the technique of layer image processing is applied to compensate the different cardiac and breathing motions. A prior phantom-based calibration is implemented to make a lookup table of correction models. A polynomial model selected from the table is used online to correct the nonlinear measurements due to x-ray physics causes. For the effect of residual contrast agent, a new workflow of triple background subtractions is proposed by introducing an initial background image. Finally, the proposed approach is validated with pre-clinical studies of porcine models.

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Early assessment of infarct size and prediction of functional recovery by quantitative myocardial blush grade in patients with acute coronary syndromes treated according to current guidelines

Riedle

Dickhaus

Erbacher

et al. 2010

Cathet Cardio Intervent

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Quantitative Automated Assessment of Myocardial Perfusion at Cardiac Catheterization

Cited by 8 publications

References 8 publications

Coronary artery tree and myocardial perfusion in patients with tako-tsubo cardiomyopathy: Evaluation with coronary digital subtraction angiography

Coronary artery tree and myocardial perfusion in patients with tako-tsubo cardiomyopathy: Evaluation with coronary digital subtraction angiography

Linear quantification correction for myocardial perfusion imaging from x-ray coronary angiography

Early assessment of infarct size and prediction of functional recovery by quantitative myocardial blush grade in patients with acute coronary syndromes treated according to current guidelines

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