Quantitative Bestimmungen mittels cyclischer Voltammetrie an der Phasengrenze zweier mischbarer Elektrolytl�sungen

Krause, J.; Umland, F.

doi:10.1007/bf01204089

Cited by 5 publications

(4 citation statements)

References 4 publications

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“…[13] Several methods were proposed, mostly for the concrete determination of quinine in soft drinks. These techniques include atomic absorption spectrometry (indirect determination) with reversed flow injection system, [14] flow through sensor with fluorimetric transduction, [15] isotachophoresis with UV and conductivity detection, [16] 4th-order derivative spectrophotometric, [17] spectrophotometric, [18] fluorimetry, [19,20] plasticized poly(vinyl chloride) membrane electrode with direct potentiometry, [21] optosensor with C 18 silica gel as substrate in conjunction with a flow injection analysis system, [22] cyclic voltammetry, [23] and immunoassay. [24] In this paper a simple, rapid, and sensitive method was developed for the routine determination of quinine based on high performance liquid chromatography (HPLC) with LIF detection.…”

Section: Fast and Sensitive New High Performance Liquidmentioning

confidence: 99%

Fast and Sensitive New High Performance Liquid Chromatography Laser Induced Fluorescence (HPLC-LIF) Method for Quinine. Comparative Study in Soft Drinks

Feás

Fente

Cepeda

2009

Journal of Liquid Chromatography & Related Technologies

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A simple, quick, and accurate new method for the determination of quinine (6 0 -methoxycinchonan-9-ol) in soft drinks is presented. The analysis is carried out using high performance liquid chromatography (HPLC), coupled laser induced fluorescence (LIF) that consisted of a 325 nm He-Cd laser and a ZETALIF detector. The chromatographic separation was performed on a Phenomenex Synergi Fusion-Reversed Phase (RP) column and allows good peak shape and symmetry in less than 1.5 min. A calibration curve ranging from 1 to 100 ng=mL was shown to be linear with a correlation coefficient (R) of 0.9999. The limit of detection of quinine was 3.2 pg on the column. The method was applied to the analysis of several beverages (n ¼ 43) containing quinine, whose analysis required minimum pretreatment before direct injection, and can therefore be used for quality control in comparison to the classical methods. Data obtained from different commercial beverages containing quinine show no homogeneous concentration of this compound. This article describes, for the first time, the successful application of HPLC coupled LIF detection for quinine determination in common beverages.

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Section: Fast and Sensitive New High Performance Liquidmentioning

confidence: 99%

Fast and Sensitive New High Performance Liquid Chromatography Laser Induced Fluorescence (HPLC-LIF) Method for Quinine. Comparative Study in Soft Drinks

Feás

Fente

Cepeda

2009

Journal of Liquid Chromatography & Related Technologies

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“…On leave from Changchun Institute of Applied Chemistry, Chinese Academy of Sciences Present address: Institut fu¨r Chemo-und Biosensorik, Mu¨nster, Germany pharmaceutical products [5], and the determination of nitrate and chloride in river water employing the flowinjection technique [6] are examples for the successful application of these new electrode systems for measurements of ions. Neutral species, e.g.…”

Section: Introductionmentioning

confidence: 99%

Amperometric detection of heavy metal ions in ion pair chromatography at an array of water/nitrobenzene micro interfaces

Wilke

Wang

Muraczewska

et al. 1996

Analytical and Bioanalytical Chemistry

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A novel amperometric detector for heavy metal ions has been developed and successfully applied for ion pair chromatography. The detector is based on the electrochemical transfer of the metal ions across an array of water/nitrobenzene micro interfaces. The ion transfer is facilitated by the neutral ionophores methylenebis(diphenylphosphineoxide) and methylenebis(di- phenylphosphinesulfide). More than eight metals are separated in less than 15 min on an RP18 column using octyl sulfonate as ion pair reagent. For the heavy metals, the limits of decision are 19(Pb(2+)), 9(Zn(2+)), 9l (Co(2+)), 8(Cd(2+)) and 1.6(Mn(2+)) microg/L. The applicability of the new method for water samples is demonstrated.

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“…1,3,4 At present, quinine is not legally permitted to be added to drinks in China. 5 In recent years, although several methods were proposed for the determination of quinine in drinks including spectrometry, 6,7 flow injection analysis, 8 cyclic voltammetry, 9 isotachophoresis, 4 micellar electrokinetic capillary chromatography, 10 and immunoassay, 11 most of which suffer from various disadvantages such as poor sensitivity, poor selectivity, time-consuming procedure, or specific requirement for an instrument, high performance liquid chromatography (HPLC) is still the most popular choice because of its facilitation of separation and detection. [12][13][14][15] However, the peak shapes of quinine were not satisfactory in most HPLC methods because of the interaction between residual silanol groups of stationary phase and quinine, which results in tailing peak and, thus, relatively poor sensitivity.…”

Section: Introductionmentioning

confidence: 99%

Determination of Quinine in Drinks by Reversed-Phase Ion-Pair Chromatography

Chen¹,

Wang²

2001

Journal of Liquid Chromatography & Related Technologies

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A reversed-phase ion-pair chromatographic method was developed for the determination of quinine in drinks. The separation was performed by an isocratic elution with 0.4% glacial acetic acid-methanol (45:55, v/v), which contained 7.5 mmol/L sodium 1-heptanesulfonate as mobile phase (1 mL/min), and detection by ultraviolet spectrometry at 236 nm and fluorimetry at 375 nm (with excitation at 334 nm). Good linearities between the concentrations of quinine and relevant peak area responses were achieved in the range of 0.1 -20 mg/mL by both detection modes.The detection limits (signal-to-noise ratio 3:1) for quinine were 0.02 µg/mL and 0.004 µg/mL for spectrometric and fluorimetric detections, respectively. The method has been successfully applied to the analysis of commercial drinks, and the average recoveries for various samples ranged from 91% to 106%.

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Quantitative Bestimmungen mittels cyclischer Voltammetrie an der Phasengrenze zweier mischbarer Elektrolytl�sungen

Cited by 5 publications

References 4 publications

Fast and Sensitive New High Performance Liquid Chromatography Laser Induced Fluorescence (HPLC-LIF) Method for Quinine. Comparative Study in Soft Drinks

Fast and Sensitive New High Performance Liquid Chromatography Laser Induced Fluorescence (HPLC-LIF) Method for Quinine. Comparative Study in Soft Drinks

Amperometric detection of heavy metal ions in ion pair chromatography at an array of water/nitrobenzene micro interfaces

Determination of Quinine in Drinks by Reversed-Phase Ion-Pair Chromatography

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