2010
DOI: 10.1364/boe.1.000176
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Quantitative comparison of the OCT imaging depth at 1300 nm and 1600 nm

Abstract: One of the present challenges in optical coherence tomography (OCT) is the visualization of deeper structural morphology in biological tissues. Owing to a reduced scattering, a larger imaging depth can be achieved by using longer wavelengths. In this work, we analyze the OCT imaging depth at wavelengths around 1300 nm and 1600 nm by comparing the scattering coefficient and OCT imaging depth for a range of Intralipid concentrations at constant water content. We observe an enhanced OCT imaging depth for 1600 nm … Show more

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Cited by 83 publications
(65 citation statements)
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References 24 publications
(21 reference statements)
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“…Some authors suggested that an imaging window at 1700 nm offers an advantage over shorter wavelengths by increasing penetration depth as well as enhancing the image contrast at deeper penetration depths by reducing multiple scattering [37]. For biological tissues, it is expected an increase in OCT imaging depth at 1600 nm compared to 1300 nm on samples with high scattering power and low water content (enamel) [38]. Otherwise at longer wavelengths, absorption increases with greater water content, which has a counterbalancing effect [37].…”
Section: Optical Coherence Tomography-the Methodsmentioning
confidence: 99%
“…Some authors suggested that an imaging window at 1700 nm offers an advantage over shorter wavelengths by increasing penetration depth as well as enhancing the image contrast at deeper penetration depths by reducing multiple scattering [37]. For biological tissues, it is expected an increase in OCT imaging depth at 1600 nm compared to 1300 nm on samples with high scattering power and low water content (enamel) [38]. Otherwise at longer wavelengths, absorption increases with greater water content, which has a counterbalancing effect [37].…”
Section: Optical Coherence Tomography-the Methodsmentioning
confidence: 99%
“…The constant Q describes the heterodyne intensity back-coupling efficiency from a scattering medium compared to that of a mirror and ranges from 0 to 1 (see section 4.3). From this analysis it can be observed that µ b can be determined by dividing (2) by (4). The backscattering coefficient is…”
Section: Single Scattering Model Of the Oct Signalmentioning
confidence: 99%
“…For our study we utilize a home-built time-domain OCT system, which is described in detail in Ref [4]. In summary, light from a Fianium light source is filtered to obtain a spectrum centered at 1300 nm, which is coupled into a fixed focus OCT setup.…”
Section: Oct Measurementsmentioning
confidence: 99%
See 1 more Smart Citation
“…Two main approaches have generally been taken in determining the optimum spectral window for OCT imaging of biological tissues: quantitative spectroscopic measurements of tissue optical properties to determine the optimum spectral window [12] [13], and direct comparison using OCT at a number of common spectral windows defined by the availability of sources [19][20] [21]. The disadvantage of the latter approach is that the comparisons tend to be qualitative as different OCT instruments have different inherent sensitivities and resolutions [22] [23].…”
Section: Introductionmentioning
confidence: 99%