2009
DOI: 10.1111/j.1540-8183.2009.00491.x
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Quantitative Coronary Angiography in the Current Era: Principles and Applications

Abstract: Coronary angiography, despite its inherent invasiveness and need for contrast media and radiographic exposure, is still routinely employed every year for the diagnostic and therapeutic management of millions of patients with or at risk for coronary artery disease. Whereas approximate visual estimation is the most common way to evaluate coronary angiography findings, since the late 1980s a number of investigators have developed and investigated methods of quantitative coronary angiography (QCA) analysis exploit… Show more

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Cited by 104 publications
(67 citation statements)
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“…Whereas no significant reductions in the risk of death or myocardial infarction could be inferred, both sirolimus-and paclitaxel-eluting stents showed substantial reductions in angiographic end-points such as late lumen loss and binary restenosis [12], as well as clinical end-points such as target lesion revascularization, and major adverse cardiac events [13]. However, the safety of such first-generation drug-eluting stents was questioned repeatedly, given the increased risk of protocol-defined stent thrombosis and the occasionally reported raised risk of death in studies with short-term dual antiplatelet therapy [14].…”
Section: First-generation Drug-eluting Stentsmentioning
confidence: 99%
“…Whereas no significant reductions in the risk of death or myocardial infarction could be inferred, both sirolimus-and paclitaxel-eluting stents showed substantial reductions in angiographic end-points such as late lumen loss and binary restenosis [12], as well as clinical end-points such as target lesion revascularization, and major adverse cardiac events [13]. However, the safety of such first-generation drug-eluting stents was questioned repeatedly, given the increased risk of protocol-defined stent thrombosis and the occasionally reported raised risk of death in studies with short-term dual antiplatelet therapy [14].…”
Section: First-generation Drug-eluting Stentsmentioning
confidence: 99%
“…Reference vessel diameter, minimal lumen diameter, percentage of diameter stenosis, and stenosis length were measured in diastolic frames from orthogonal projections according to validated protocols 8 for both intermediate and severe stenoses.…”
Section: Methodsmentioning
confidence: 99%
“…However differences in results using FP systems compared with classic image intensifier-based imaging systems were shown to be clinically not significant (Tuinenburg et al, 2006). In the common clinical practice there are different computer systems for QCA that have been validated: among them the most commonly employed are CAAS (PIE Medical, Maastricht, The Netherlands) and QAngio XA (Medis, Leiden, The Netherlands) (Garrone et al, 2009). …”
Section: Two-dimensional Qcamentioning
confidence: 99%
“…Therefore, it is possible to determine MLD and DS for each one of the three segments considered. Several angiographic phenomena can bias QCA and lead to overestimation or underestimation of QCA parameters such as acute or chronic thrombus, extensive calcium deposits, dissections, diffuse disease, and slow flow, therefore it is of paramount importance to add a qualitative analysis for lesion features to any QCA analysis (Garrone et al, 2009). …”
Section: Parametersmentioning
confidence: 99%