Quantitative determination of conjugated estrogens in formulations by capillary GLC

Mechanisms of Cardioprotection by Estrogens

“…0037-97271981217 1-0023$10.5010 Copyright 0 1998 by the Society for Experimental Biology and Medicine essential to understand structural differences among estrogens used in therapy and appreciate the differences in their biological activity and a few aspects of their metabolism. CEE represents a mixture of conjugated estrogens isolated from the urine of pregnant mares and contains at least 9 major components (6,7). Among these, estrone sulphate is the predominant estrogen (about 45%) with a significant amount of ring B unsaturated equine estrogens (predominantly 17a-dihydroequilin, equilin, equilenin amounting to nearly 51%), and minor amounts of both 17p and 17a estradiol (<4%).…”