Quantitative determination of formic acid in apple juices by 1H NMR spectrometry

Berregi, Iñaki; Campo, Gloria del; Caracena, Raúl; Miranda, José I.

doi:10.1016/j.talanta.2006.12.031

Cited by 56 publications

(31 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…NMR has the ability to serve as an invaluable tool for the compositional analysis of foods, not only due to its ability to provide important information for structural elucidation, but also for its quantitative nature. NMR has been effectively used for the analysis of several classes of compounds including lipids (Dais & Hatzakis, ; Monakhova & Diehl, , ; Siddiqui et al., ; Tsiafoulis et al., ), carbohydrates (Kazalaki et al., ; Merkx, Hong, Ermacora, & van, ; Singh, Kumar, Srivastava, Deepak, & Singh, ; Spraul et al., , ), amino acids (Belton et al., ), alcohols (Hatzakis, Archavlis, & Dais, ; Nilsson et al., ), organic acids (Berregi, del Campo, Caracena, & Miranda, ), polyphenols (Agiomyrgianaki & Dais, , ; Charisiadis, Exarchou, Troganis, & Gerothanassis, ), vitamins (Ackermann et al., ; Dais et al., ; Shumilina, Ciampa, Capozzi, Rustad, & Dikiy, ; Vaysse et al., ), terpenes (Dais, Plessel, Williamson, & Hatzakis, ), phospholipids (Hatzakis, Koidis, Boskou, & Dais, ; Kaffarnik, Ehlers, Gröbner, Schleucher, & Vetter, ), colorants (Englert, ; Scotter, ; Venkatachalam et al., ; Berké, Chèze, Vercauteren, & Deffieux, ), and contaminants (Lachenmeier et al., ) in a variety of foods, such as oils (Dais & Hatzakis, ; Siddiqui et al., ), beverages (Kidrič, ; Ryu, Koda, Miyaka, & Tanokura, ; Santos, Fonseca, Lião, Alcantara, & Barison, ; Zurriarrain et al., 2015), meats (García‐García et al., ), dairy products (Gangwar, Singh, & Deepak, ; Hu, Furihata, Ito‐Ishida, Kaminogawa, & Tanokura, ; Maher & Rochfort, ; Murgia, Mele, & Monduzzi, ; Scano et al., ; Tociu et al., ), and infant formula (Zhao et al., ). For the structural characterization of various food components, the application of 2D techniques is often required.…”

Section: Fundamentals Of Nmr Spectroscopy‐relevance To Food Sciencementioning

confidence: 99%

Nuclear Magnetic Resonance (NMR) Spectroscopy in Food Science: A Comprehensive Review

Hatzakis

2018

Comp Rev Food Sci Food Safe

281

126

View full text Add to dashboard Cite

Nuclear magnetic resonance (NMR) spectroscopy is a robust method, which can rapidly analyze mixtures at the molecular level without requiring separation and/or purification steps, making it ideal for applications in food science. Despite its increasing popularity among food scientists, NMR is still an underutilized methodology in this area, mainly due to its high cost, relatively low sensitivity, and the lack of NMR expertise by many food scientists. The aim of this review is to help bridge the knowledge gap that may exist when attempting to apply NMR methodologies to the field of food science. We begin by covering the basic principles required to apply NMR to the study of foods and nutrients. A description of the discipline of chemometrics is provided, as the combination of NMR with multivariate statistical analysis is a powerful approach for addressing modern challenges in food science. Furthermore, a comprehensive overview of recent and key applications in the areas of compositional analysis, food authentication, quality control, and human nutrition is provided. In addition to standard NMR techniques, more sophisticated NMR applications are also presented, although limitations, gaps, and potentials are discussed. We hope this review will help scientists gain some of the knowledge required to apply the powerful methodology of NMR to the rich and diverse field of food science.

show abstract

Section: Fundamentals Of Nmr Spectroscopy‐relevance To Food Sciencementioning

confidence: 99%

Nuclear Magnetic Resonance (NMR) Spectroscopy in Food Science: A Comprehensive Review

Hatzakis

2018

Comp Rev Food Sci Food Safe

281

126

View full text Add to dashboard Cite

show abstract

“…The results obtained when applying NMR procedures were compared to those obtained using enzymatic methods and both were in close agreement. 111 Formic acid content in apple juices of five different cider varieties was assessed using qHNMR by Berregi et al 112 …”

Section: Applications Of Qhnmrmentioning

confidence: 99%

Quantitative ¹H NMR. Development and Potential of an Analytical Method: An Update

et al. 2012

View full text Add to dashboard Cite

Covering the literature from mid-2004 until the end of 2011, this review continues a previous literature overview on quantitative 1 H NMR (qHNMR) methodology and its applications in the analysis of natural products. Among the foremost advantages of qHNMR is its accurate function with external calibration, the lack of any requirement for identical reference materials, a high precision and accuracy when properly validated, and an ability to quantitate multiple analytes simultaneously. As a result of the inclusion of over 170 new references, this updated review summarizes a wealth of detailed experiential evidence and newly developed methodology that supports qHNMR as a valuable and unbiased analytical tool for natural product and other areas of research.

show abstract

“…These loadings were still lower than the breakthrough point of the NeedlEX given the significant linearity. The concentration range in these experiments is equivalent to those found in most of the environmental samples and some beverages such as apple juice, fruit syrup, and honey []. It shows the potential of the NeedlEX extraction to samples from a wide range of sources.…”

Section: Resultsmentioning

confidence: 71%

Needle trap extraction for GC analysis of formic and acetic acids in aqueous solution

Lee

Huang

Lou

et al. 2012

J of Separation Science

View full text Add to dashboard Cite

Formic and acetic acids are ubiquitous in the environment, food, and most of the natural products. Extraction of the acids from aqueous solution is required for their isotope analysis by the gas chromatography-isotope ratio mass spectrometry. To this objective, we have previously developed a purge-and-trap technique using the dynamic solid-phase microextraction technology, the NeedlEX. The extraction efficiency, however, remains unexamined. Here, we address this question using the flame ionization detector and isotope ratio mass spectrometer while comparing it with that of the CAR/PDMS fiber. The results show that the NeedlEX is applicable at a wide range of concentration through coordination of purge volume given the minimum amount 3.7 ng and 1.8 ng of formic and acetic, respectively, is extracted. The efficiency of NeedlEX was 6-7 times lower than the fiber at 1000 μg/mL depending on the analyte. It is, however, superior to the latter at 10 μg/mL or less owing to its lower detection limit. The extraction efficiency of both acids is equivalent in molar amount. This is, however, disguised by the different response of the flame ionization detector. The isotope ratio mass spectrometor overcomes this problem but is compromised by relatively large errors. These results are particularly useful for isotopic analysis of carboxylic acids.

show abstract

Quantitative determination of formic acid in apple juices by 1H NMR spectrometry

Cited by 56 publications

References 22 publications

Nuclear Magnetic Resonance (NMR) Spectroscopy in Food Science: A Comprehensive Review

Nuclear Magnetic Resonance (NMR) Spectroscopy in Food Science: A Comprehensive Review

Quantitative ¹H NMR. Development and Potential of an Analytical Method: An Update

Needle trap extraction for GC analysis of formic and acetic acids in aqueous solution

Contact Info

Product

Resources

About

Quantitative determination of formic acid in apple juices by 1H NMR spectrometry

Cited by 56 publications

References 22 publications

Nuclear Magnetic Resonance (NMR) Spectroscopy in Food Science: A Comprehensive Review

Nuclear Magnetic Resonance (NMR) Spectroscopy in Food Science: A Comprehensive Review

Quantitative 1H NMR. Development and Potential of an Analytical Method: An Update

Needle trap extraction for GC analysis of formic and acetic acids in aqueous solution

Contact Info

Product

Resources

About

Quantitative ¹H NMR. Development and Potential of an Analytical Method: An Update