Quantitative determination of major polyphenol constituents in pomegranate products

Qu, Wenjuan; Breksa, Andrew P.; Pan, Zhongli; Ma, Haile

doi:10.1016/j.foodchem.2011.11.106

Cited by 120 publications

(95 citation statements)

References 17 publications

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“…[10][11][12] Hydrolyzable tannins including ellagitannins and gallotannins consist of the common constituents present in pomegranate, and punicalagin is the major hydrolyzable tannin present in pomegranates. [13][14][15][16] The juice of arils consist ofwater, sugars such as glucose, sucrose, and fructose, 17 1.5% pectin, organic acids including citric, malic, tartaric, succinic, fumaric and ascorbic acid. 18 Pills also have hydroxybenzoic containing pomegranate extract potently delayed the onset and reduced the incidence of collagen-induced arthritis and severity of arthritis was significantly lower in extract fed animals.…”

Section: Chief Constituents Of Pomegranatementioning

confidence: 99%

Active Constituents of Pomegranates (Punica granatum) as Potential Candidates in the Management of Health through Modulation of Biological Activities

Rahmani¹,

Alsahli²,

Almatroodi³

2017

190

183

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Pomegranates fruits have innumerable health benefits and its implication in diseases cure have been widely recognized since ancient time. Moreover, pomegranate fruits, seeds and peels are intensively used in traditional medicine as a natural therapy. It contains numerous valuable ingredients such as flavonoids, ellagitannin, punicalagin, ellagic acid, vitamins and minerals. The principal constituents including punicalagins and ellagitannin are responsible for immeasurable health benefits due to its strong antioxidant activity. Additionally, constituents of pomegranate show health promoting effect through the modulation of physiological and biochemical pathways. Recent evidences suggested that pomegranates fruits, peels and seeds illustrate therapeutics implications in health management via inhibition of free radical effect and modulation of enzymes activity linked with diseases development and progression. In this review, we summarize the therapeutic role of pomegranate fruits, seeds and peels in the health managements based on in vitro and in vivo studies.

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Section: Chief Constituents Of Pomegranatementioning

confidence: 99%

Active Constituents of Pomegranates (Punica granatum) as Potential Candidates in the Management of Health through Modulation of Biological Activities

Rahmani¹,

Alsahli²,

Almatroodi³

2017

190

183

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“…Quantification of ellagic acid, gallic acid and punicalagins Pomegranate is reported to contain a wide array of compounds with diverse range of bioactivities (Gil et al 2000;Kulkarni and Aradhya 2005;Mousavinejad et al 2009;Qua et al 2012). Of these, three main constituents viz., ellagic acid, gallic acid and punicalagin possess immense pharmacological properties (Qua et al 2012).…”

Section: Abts Radical Scavenging Activity Of Various Extractsmentioning

confidence: 99%

“…Of these, three main constituents viz., ellagic acid, gallic acid and punicalagin possess immense pharmacological properties (Qua et al 2012). During the past years, a few efforts were made for identification and quantification of these major polyphenolic compounds from pomegranate (Seeram et al 2005;Qua et al 2012).…”

Section: Abts Radical Scavenging Activity Of Various Extractsmentioning

confidence: 99%

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Influence of the solvents on the extraction of major phenolic compounds (punicalagin, ellagic acid and gallic acid) and their antioxidant activities in pomegranate aril

et al. 2014

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Phenolic compounds of fruits have been shown to maintain human health. However, the relative amounts of phenolic compounds and the variation in the types of phenolics are still poorly understood. The purpose of this study was to investigate the most effective solvent for extracting the potent antioxidant compounds, especially phenolics from pomegranate aril. Pomegranate aril was subjected to extraction using different solvents viz., water, ethanol, acetone and diethyl ether either alone or in combination, and the extraction yield, total phenolic contents, and antioxidant activity were investigated. The extracts derived from various solvents were also analysed using high performance liquid chromatography (HPLC) for quantification of major polyphenols (punicalagins, ellagic acid and gallic acid) of pomegranate. Amongst the tested solvents, combination of ethanol, diethyl ether and water (8:1:1) extract exhibited the highest 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging power (IC50 = 10.12 μg mL-1). Further, HPLC analysis of different extracts revealed that ethanol, diethyl ether and water (8:1:1) mixture contained significantly higher (p<0.05) amounts of punicalagin A (1.06 μg mg-1 extract), punicalagin B (2.07± 0.03 μg mg-1 extract), ellagic acid (34.5 μg mg-1 extract) and gallic acid (3.37 μg mg-1 extract) in comparison to the other solvents used for extraction. The results demonstrate that pomegranate aril is a good source of phenolic compounds with high antioxidant activity and the antioxidant activity is dependent on the type of solvent system that extracts different phenolic compounds with varying polarity. The solvent extracts that showed effective antioxidants activities have the potential for application in suitable food products.

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“…ISSN 2308-8303 идентификации компонентов были времена удер-живания исследуемых веществ, УФ-спектры, базы данных и обзорные статьи по основным спект-ральным характеристикам дубильных кислот [13]. Анализ проб выполняли на аналитической ВЭЖХ-системе, состоящей из жидкостного хроматогра-фа «Agilent 1200» с диодно-матричным детекто-ром и системы для сбора и обработки хромато-графических данных ChemStation.…”

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Synthesis and the antiresistant activity of acylated and supramolecular derivatives of ellagic acid

Alhussein¹,

Martynov²

2014

J. org. pharm. chem.

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Целью исследований было получение новых, более растворимых и биологически активных произво-дных эллаговой кислоты через ацилирование фенольных гидроксилов и получение супрамолекуляр-ных комплексов с циклодекстринами, изучение способности синтезированных производных снимать резистентность микроорганизмов к аминогликозидным антибиотикам (на примере гентамицина

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Quantitative determination of major polyphenol constituents in pomegranate products

Cited by 120 publications

References 17 publications

Active Constituents of Pomegranates (Punica granatum) as Potential Candidates in the Management of Health through Modulation of Biological Activities

Active Constituents of Pomegranates (Punica granatum) as Potential Candidates in the Management of Health through Modulation of Biological Activities

Influence of the solvents on the extraction of major phenolic compounds (punicalagin, ellagic acid and gallic acid) and their antioxidant activities in pomegranate aril

Synthesis and the antiresistant activity of acylated and supramolecular derivatives of ellagic acid

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