Quantitative determination of sulfanilamide in sodium sulfacetamide raw material and ophthalmic solutions by high-performance liquid chromatography

Validated chromatographic methods for the simultaneous determination of a ternary mixture of sulfacetamide sodium and two of its official impurities; sulfanilamide and dapsone

“…Chromatographic techniques are considered the most suitable and commonly used analytical techniques for determination of drug substances in presence of impurities in pharmaceutical analysis [7][8][9]. Several chromatographic methods were reported for the simultaneous determination of sulfacetamide and sulfanilamide [10][11][12][13][14]. However, no method was reported in the literature for the simultaneous determination of ternary mixture of sulfacetamide sodium, sulfanilamide and dapsone.…”

Determination of sulphathiazole and sulphanilamide by photochemically induced fluorescence and first-derivative fluorescence

“…For determining sulphanilamide, chromatographic methods have the leading position, by using mass spectrometric detection [4,5], being applied in biological fluids [6], pharmaceutical preparations [6][7][8][9] and foods [10,11]. Another techniques employed are spectrophotometry [6,12,13] with flow-injection analysis (FIA) [14] and fluorescence [15] with flow-injection analysis [16].…”