Quantitative evaluation of corneal epithelial oedema by confocal microscopy

Abstract

The BCL index was increased after cataract surgery and in eyes affected by bullous keratopathy, conditions associated with corneal epithelial oedema. This quantitative measure obtained by confocal microscopy may prove useful in the clinical evaluation of corneal epithelial oedema.

Effect of preoperative duration of stromal edema in bullous keratopathy on early visual acuity after endothelial keratoplasty

“…Given that such changes are difficult to detect by slitlamp microscopy, we recommend that the cornea of patients with endothelial decompensation be examined for pathologic changes at the anterior stroma by in vivo laser confocal microscopy. We previously found that the intensity of in vivo confocal microscopic images of the corneal epithelium is increased in patients with bullous keratopathy 21 ; thus, it may be difficult to detect pathologic changes in the anterior stroma in these cases. Although DSAEK yields a CDVA of close to 20/20 in many patients, some patients in Group A in our study did not achieve such a favorable visual outcome.…”

Normative Database for Corneal Backscatter Analysis by In Vivo Confocal Microscopy

“…4A, 4B). 31 The EV may prove more sensitive than CCT in the detection of corneal edema, and therefore may be an important parameter in the evaluation of the cornea in Fuchs endothelial dystrophy, before cataract surgery. Likewise, subepithelial fibrosis in Fuchs endothelial dystrophy may be staged with the SP, to estimate the effect of Descemet stripping automated endothelial keratoplasty (DSAEK) on the postoperative best corrected visual acuity (Figs.…”

Corneal confocal microscopy alterations in Sjögren's syndrome dry eye

“…), cataract surgery (phacoemulsification) (Morishige et al. ), herpetic stromal keratitis (Hillenaar et al. ) or corneal haze (McLaren et al.…”