Quantitative evaluation of fetal right and left ventricular fractional area change using speckle‐tracking technology

DeVore, G. R.; Klas, Berthold; Satou, Gary; Sklansky, Mark

doi:10.1002/uog.19048

Cited by 42 publications

(96 citation statements)

References 33 publications

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“…We have previously published our findings evaluating global, circumferential, and longitudinal assessments of the RV and LV using speckle‐tracking software, which are important diagnostic tools used in evaluations of the heart in neonatal and pediatric patients . One could pose the question as to why it would be necessary to measure the EDV and ESV and compute the SV, SV/kg, CO/kg, and EF.…”

Section: Discussionmentioning

confidence: 99%

“…We have previously published our findings evaluating global, circumferential, and longitudinal assessments of the RV and LV using speckletracking software, which are important diagnostic tools used in evaluations of the heart in neonatal and pediatric patients. 5,6,8,[32][33][34] One could pose the question as to why it would be necessary to measure the EDV and ESV and compute the SV, SV/kg, CO/kg, and EF. The reason is because fetal disease states associated with alterations of cardiac structure (aortic stenosis and coarctation of the aorta) or cardiac function (cardiomyopathy, fetal anemia, and IUGR) may have implications Figure 6.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of Fetal Left Ventricular Size and Function Using Speckle‐Tracking and the Simpson Rule

DeVore

Klas²,

Satou

et al. 2018

J of Ultrasound Medicine

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Objectives This study was conducted to evaluate left ventricular (LV) size and function in healthy fetuses and to test a cohort of fetuses at risk for abnormal function using speckle‐tracking software. Methods Two hundred control fetuses were examined between 20 and 40 weeks’ gestation. With the use of offline speckle‐tracking software, the end‐diastolic and end‐systolic volumes were measured and the following computed: stroke volume (SV), SV per kilogram, cardiac output (CO), CO per kilogram, and ejection fraction. These were regressed against 7 independent variables related to the size, weight, and age of the fetuses. Five fetuses with risk factors for LV dysfunction were examined to sample the validity of the data from the control group. Results The R2 values for measurements of the end‐diastolic volume, SV, and CO correlated with the 7 independent variables of fetal size and age (0.7–0.78), whereas the SV/kg, CO/kg, and ejection fraction had lower R2 values (0.02–0.1). The measurements were normally distributed (Shapiro‐Wilke > 0.5). The 5 fetuses at risk for abnormal LV function had measurements of LV size and function that were consistent with the expected pathologic condition. Conclusions Speckle tracking can provide a comprehensive evaluation of the size and function of the fetal LV.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Evaluation of Fetal Left Ventricular Size and Function Using Speckle‐Tracking and the Simpson Rule

DeVore

Klas²,

Satou

et al. 2018

J of Ultrasound Medicine

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“…Two hundred control fetuses with accurate 1st-and/or 2ndtrimester dating ultrasound were examined between 20 and 40 weeks of gestation, as described in prior publications [8,10,11,[13][14][15][16][17][18]. The fetuses were not at risk for congenital heart defects or growth restriction and were free from ultrasound-detected malformations and growth disturbance at the time of the examination [19].…”

Section: Normal Study Groupmentioning

confidence: 99%

“…We hypothesized that, in addition to changes in ventricular disproportion, downstream obstruction in the aortic arch could alter the shape and size of the global 4-chamber view (4-CV), RV, and LV, and also RV and LV contractility in subtle ways detected only by detailed analysis of these parameters. The purpose of this study was to evaluate the following measurements between normal control fetuses and fetuses with postnatally confirmed CoA, irrespective of the presence or absence of associated cardiac abnormalities: (1) the shape and size of the global 4-CV [8][9][10], (2) the shape and size of the RV and LV chambers [11][12][13], (3) the global, longitudinal, and transverse contractility of the RV and LV [14][15][16][17], and (4) the stroke volume, cardiac output, and ejection fraction of the LV [18].…”

Section: Introductionmentioning

confidence: 99%

Aortic Coarctation: A Comprehensive Analysis of Shape, Size, and Contractility of the Fetal Heart

et al. 2019

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Background: An integrated assessment of the size and shape of the 4-chamber view (4-CV) and right and left ventricles (RV and LV) as well as the function of the RV and LV in fetuses with coarctation of the aorta (CoA) has not yet been conducted. Objectives: We evaluated the size and shape of the 4-CV, RV, and LV, and function of the RV and LV, to identify a profile for fetuses with CoA when compared to a control population. Methods: 50 CoA fetuses were compared to 200 controls. This was a retrospective case series comparing the 4-CV of CoA fetuses and controls. The 4-CV end-diastolic area, length, width, and sphericity index were measured to determine the configuration of the 4-CV. Speckle-tracking analysis was used to compute the RV and LV end-diastolic area, length, 24-segment sphericity index, 24-segment transverse width, and the following functional parameters:(1) fractional area change; (2) global, lateral, and septal strain;(3) basal-apical, lateral, and septal annular displacement and fractional shortening; and (4) 24-segment transverse width fractional shortening. Using 5 and 95% reference intervals, the CoA fetal measurements were classified; from these, the odds ratio was computed between the fetuses with CoA and the controls. p < 0.05 was considered significant. Results: In fetuses with CoA, the 4-CV was spherical in shape, increased in area and width, and decreased in length. Abnormal CoA sphericity indices reflected a flatter LV and a more spherical RV. The LV area, length, and width, and RV length were decreased. The transverse width of the RV was increased. RV and LV global, longitudinal, and transverse contractility were depressed. Conclusions: The results demonstrate previously unappreciated differences in the shape, size, and function of the heart in fetuses with CoA. These differences may assist examiners in identifying fetuses with CoA.

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“…Lastly, we have reported a number of cardiac measurements derived from speckle‐tracking analysis of the right and left ventricular endocardium that analyze ventricular size, shape and contractility. This analysis, a relatively new adaptation of speckle‐tracking assessment, enables the examiner to obtain numerous cardiac measurements from a single endocardial tracing of each ventricle, which takes less than 3 min, and is now commercially available on ultrasound platforms dedicated primarily to fetal evaluation.…”

mentioning

confidence: 99%

Using speckle‐tracking echocardiography to assess fetal myocardial deformation: are we there yet? Yes we are!

DeVore

Satou

Sklansky

2019

Ultrasound in Obstet & Gyne

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Quantitative evaluation of fetal right and left ventricular fractional area change using speckle‐tracking technology

Abstract: This study reports results from measuring the FAC of the right and left ventricles, and demonstrates a correlation with longitudinal fractional shortening (LFS) and transverse fractional shortening (TFS).

Cited by 42 publications

References 33 publications

Evaluation of Fetal Left Ventricular Size and Function Using Speckle‐Tracking and the Simpson Rule

Evaluation of Fetal Left Ventricular Size and Function Using Speckle‐Tracking and the Simpson Rule

Aortic Coarctation: A Comprehensive Analysis of Shape, Size, and Contractility of the Fetal Heart

Using speckle‐tracking echocardiography to assess fetal myocardial deformation: are we there yet? Yes we are!

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