Quantitative evaluation of norcholesterol scintigraphy, CT attenuation value, and chemical-shift MR imaging for characterizing adrenal adenomas

Abstract

The norcholesterol uptake rate was reliable for characterization of adenomas among adrenal masses of >or=2.0 cm. CT attenuation value and MR suppression index were well correlated with each other, and were useful regardless of mass size.

Contralateral adrenal suppression on adrenocortical scintigraphy provides good evidence showing subclinical cortisol overproduction from unilateral adenomas

“…in patients with adrenal masses to identify cortisolproducing adenomas including SCS, but these studies have been performed on relatively small numbers of subjects [16][17][18]. To date, no study has examined which adrenal uptake rate on ACS (the tumor or nontumor side) reflects the cortisol production ability of the adenoma.…”

Contribution of MRI in lung cancer staging

“…In contrast, nonadenomas do not show signal loss on out-of-phase imaging (23). Recent studies have shown that 60 to 89 percent of lesions measuring between 10 and 30 HU on unenhanced CT can be characterized using chemical shift MRI (24,25).…”

Surgical approach in adrenal incidentalomas: Report of thirteen cases and review of the literature

“…In recent years, particularly with the widespread use of ultrasonography (US), computed tomography (CT) and magnetic resonance imaging (MRI), there has been a marked increase in the overall incidence of incidentalomas. Adrenal incidentalomas should primarily be assessed in terms of the lesion's hormonal activity and malignant potential (5,6).…”