Quantitative Organic Microanalysis

Pregl, Fritz; Fylemen, Ernest

doi:10.1016/b978-0-12-395686-6.x5001-6

Cited by 39 publications

(2 citation statements)

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“…The composition of poly(VEP-co-GMA)-graft-mPEG was determined using elemental [ 15 ] and functional analysis [ 16 ]. The structure of polymer was also confirmed by NMR spectroscopy.…”

Section: Methodsmentioning

confidence: 99%

Cannabimimetic N-Stearoylethanolamine as “Double-Edged Sword” in Anticancer Chemotherapy: Proapoptotic Effect on Tumor Cells and Suppression of Tumor Growth versus Its Bio-Protective Actions in Complex with Polymeric Carrier on General Toxicity of Doxorubicin In Vivo

et al. 2023

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This study reports a dose-dependent pro-apoptotic action of synthetic cannabimimetic N-stearoylethanolamine (NSE) on diverse cancer cell lines, including multidrug-resistant models. No antioxidant or cytoprotective effects of NSE were found when it was applied together with doxorubicin. A complex of NSE with the polymeric carrier poly(5-(tert-butylperoxy)-5-methyl-1-hexen-3-yn-co-glycidyl methacrylate)-graft-PEG was synthesized. Co-immobilization of NSE and doxorubicin on this carrier led to a 2-10-fold enhancement of the anticancer activity, particularly, against drug-resistant cells overexpressing ABCC1 and ABCB1. This effect might be caused by accelerated nuclear accumulation of doxorubicin in cancer cells, which led to the activation of the caspase cascade, revealed by Western blot analysis. The NSE-containing polymeric carrier was also able to significantly enhance the therapeutic activity of doxorubicin in mice with implanted NK/Ly lymphoma or L1210 leukemia, leading to the complete eradication of these malignancies. Simultaneously, loading to the carrier prevented doxorubicin-induced elevation of AST and ALT as well as leukopenia in healthy Balb/c mice. Thus, a unique bi-functionality of the novel pharmaceutical formulation of NSE was revealed. It enhanced doxorubicin-induced apoptosis in cancer cells in vitro and promoted its anticancer activity against lymphoma and leukemia models in vivo. Simultaneously, it was very well tolerated preventing frequently observed doxorubicin-associated adverse effects.

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“…The composition of poly(VEP-co-GMA)-graft-mPEG was determined using elemental [ 15 ] and functional analysis [ 16 ]. The structure of polymer was also confirmed by NMR spectroscopy.…”

Section: Methodsmentioning

confidence: 99%

Cannabimimetic N-Stearoylethanolamine as “Double-Edged Sword” in Anticancer Chemotherapy: Proapoptotic Effect on Tumor Cells and Suppression of Tumor Growth versus Its Bio-Protective Actions in Complex with Polymeric Carrier on General Toxicity of Doxorubicin In Vivo

et al. 2023

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“…Because, the copper removes excess unreacted oxygen during the combustion, reduces the NO x in the nitrogen, and converts any CO present in the gas into CO 2 . [155,156] Finally, the detection of gasses and quantification is carried out by partial separation by frontal chromatography or series of separate infrared thermal conductivity detection of individual combustion gas compounds. This method is very helpful to quantify the sulfur content present in the sulfuric acid hydrolyzed CNCs.…”

Section: Chn Analysismentioning

confidence: 99%

A comprehensive review on cellulose nanocrystals and cellulose nanofibers: Pretreatment, preparation, and characterization

Nagarajan¹,

Ramanujam²,

Sanjay

et al. 2021

Polymer Composites

218

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Crafting ecological materials from green resources is posing a significant challenge for the researchers and scientists around the globe and has resulted in the development of nanocellulose materials, which has paved the way for enriching the basic knowledge and many opportunities on developing biobased materials. This has augmented the utilization of carbohydrate-based organic materials and successfully replacing conventional nonrenewable materials. Cellulose nanomaterials (CNMs) belonging to the newer emerging field of nanomaterials are finding increasing interest among the investigators owing to their environmentally sustainable characteristics like biodegradability, biocompatibility, and potential availability in abundance at a cheaper price. The present review article intends to provide a detailed insight about the advancements and various challenges postured in the field of cellulose nanocrystals (CNCs) and cellulose nanofibers (CNFs). The article further discusses about different cellulose fiber extraction sources and their methods, purification processes employed, various sample preparation and drying techniques used for CNCs and CNFs. The article also outlines the various characterization methods practiced for scrutinizing CNCs and CNFs when used in polymer matrix composites. Finally, the benefits of using the CNMs in several potential applications such as paper, oil and gas industries, food packaging and structural sectors, conductive ink and water purification areas, medical and printed electronic fields are highlighted in this extensively reviewed article.

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