Quantitative Prediction of Agarotetrol in Chinese Eaglewood Using Near Infrared Spectroscopy

Abstract

To overcome the numerous disadvantages of existing testing technology, a novel, fast, nondestructive, and quantitative technology for quality evaluation of Chinese eaglewood (CE) based on near-infrared (NIR) technology was proposed in this study. The extractives of CE were qualitatively analyzed to determine the types of volatile compounds using gas chromatography-mass spectroscopy and were quantitatively determined using high performance liquid chromatography (HPLC). Agarotetrol was quantitatively determined by the HPLC analysis. The content was found to range widely from 0.016 to 0.104 mg/g. A quantitative prediction model aimed at quality control was proposed based on the qualitative and quantitative results coupled with a partial least squares regression. The coefficient of correlation and residual predictive deviation of the prediction model were determined to be 0.9697 and 5.77, respectively. The practical tests showed an average error of 0.000327%, which indicated that the method was able to provide a novel, quick, and effective quality evaluation of CE.

Extraction of pharmaceutical composition from Chinese eaglewood and its therapeutic efficacy

“…Later, investigators conducted further research and found that Chinese eaglewood extracts can regenerate impaired nerve cells, which exert compensatory effects. (Ding et al 2018).…”