Quantitative Reference Ranges for Fasting Profiles and Oral Glucose Tolerance Test for Healthy Adults in Metropolitan Region of Nairobi, Kenya

Abstract

an online international journal allowing free unlimited access to abstract and full-text of published articles. The journal is devoted to the promotion of health sciences and related disciplines (including medicine, pharmacy, nursing, biotechnology, cell and molecular biology, and related engineering fields). It seeks particularly (but not exclusively) to encourage multidisciplinary research and collaboration among scientists, the industry and the healthcare professionals. It will also provide an international forum for the communication and evaluation of data, methods and findings in health sciences and related disciplines. The journal welcomes original research papers, reviews and case reports on current topics of special interest and relevance. All manuscripts will be subject to rapid peer review. Those of high quality (not previously published and not under consideration for publication) will be published without delay. The maximum length of manuscripts should normally be 10,000 words (20 single-spaced typewritten pages) for review, 6,000 words for research articles, 3,000 for technical notes, case reports, commentaries and short communications. Submission of Manuscript:The International Journal of Health Research uses a journal management software to allow authors track the changes to their submission. All manuscripts must be in MS Word and in English and should be submitted online at http://www.ijhr.org. Authors who do not want to submit online or cannot submit online should send their manuscript by e-mail attachment (in single file) to the editorial office below. Submission of a manuscript is an indication that the content has not been published or under consideration for publication elsewhere. Authors may submit the names of expert reviewers or those they do not want to review their papers. Purpose: To establish quantitative reference ranges for fasting profiles and oral glucose tolerance test for healthy adults in metropolitan region of Nairobi. Methods: A prospective study carried out on 871 healthy subjects from the metropolitan region of Kenya. Results: The fasting profile parameters investigated were fasting blood glucose (FBG), total cholesterol (TC) triglycerides (TG), high density lipoprotein cholesterol (HDLC), low density lipoprotein cholesterol (LDLC) and TC/HDLC ratio. In addition, oral glucose tolerance test (OGTT) was also investigated. Eight hundred and seventy one (871) healthy study subjects were involved in the study. Established reference ranges were as follows: FBG (venous whole blood) (2.1 -5.7) mmol/L, TC (2.9 -6.4) mmol/L, TG (0.44-2.44), HDL C (1.1 -2.1) mmol/L, LDLC (1.1 -4.3) mmol/L, TC/HDLC ratio (1.1 -5.4). Established reference ranges for oral glucose tolerance test (OGTT) were as follows: baseline/fasting blood glucose capillary whole blood (3.2-5.4) mmol/L, half hour (4.7-8.9) mmol/L, one hour (4.4-9.8) mmol/L, one hour and half (4-8.1) mmol/L and two hours (3.4-7.2) mmol/L. Results for gender differences for the studied parameters were as follows: FBG (p=0.124), TC (p=0.20...