Quantitative thallium-201 imaging: Limitations in detecting pathophysiologically significant obstructive coronary artery disease

Madeira, Samuel W.; Bodenheimer, Monty M.; Banka, Vidya S.; Agarwal, Jai B.; Weintraub, William S.; Helfant, Richard H.

doi:10.1016/0002-8703(84)90691-4

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Cited by 3 publications

(1 citation statement)

References 17 publications

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“…Divergent results seem to be partly due to differences in the methods used. Among quantitative methods, wash-out characteristics alone are incapable of detecting the presence of significant coronary lesions (26,33). Resting kinetics pose similar problems (15,26,27,40).…”

Section: Other Problemsmentioning

confidence: 99%

Myocardial Scintigraphy with 201Tl: II. Clinical Applications (Coronary Heart Disease)

Klepzig²

1987

Nuklearmedizin

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Section: Other Problemsmentioning

confidence: 99%

Myocardial Scintigraphy with 201Tl: II. Clinical Applications (Coronary Heart Disease)

Klepzig²

1987

Nuklearmedizin

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Reproducibility of myocardial thallium‐201 washout in studies applying a standardized dipyridamole stress protocol

Siostrzonek¹,

Dudczak²,

Schmoliner³

1987

Clinical Cardiology

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Sllmmary: Thallium-201 (20iT1) washout analysis was proposed as an adjunctive tool to improve the detection of coronary artery disease (CAD). Since reproducibility of 'QiTI washout in dipyridamole (DPM) stress studies is unknown, this item was evaluated in 32 patients (24 with CAD, 8 without CAD), who were scintigraphed twice within 1-2 weeks. At 2 minutes following DPM infusion (0.5 ing/kg/S min), 2 niCi 201T1 were injected. Global and segniental washout were calculated by comparing circumfcrential profiles of respective background-corrected stress (IeJt mtcrior oblique (LAO) 45": 8 min postinfusion (p.i.), 35 niin p.i.; anterior (ANT): 17 min p.i.; LAO 70": 26 min p.i.) and redistribution (4 h p.i.) images. Whereas \isu;il findings were comparable for study I and 11. rcprc>ducibility of 2oiT1 washout was low, indicated by comparing variances aniong patients with variance bctween studies. which were 28.8 and 71.2% of total vari-;iiicc. respectively. Mean differences of segmental washout hetwt.cn the studies ranged from 9.75 t o 19.24% with only minor differences with regard to the different views and scgmcnts evaluated. Variability was lower using the intcniicdiate instead o f the initial scintigrarn as reference for the redistribution image (12.87&11.64% VS. 18..59$14.43%, n=8S; p

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Longitudinal (Natural History) Studies of Silent Myocardial Ischemia

Bigger

1988

Developments in Cardiovascular Medicine

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Quantitative thallium-201 imaging: Limitations in detecting pathophysiologically significant obstructive coronary artery disease

Cited by 3 publications

References 17 publications

Myocardial Scintigraphy with 201Tl: II. Clinical Applications (Coronary Heart Disease)

Myocardial Scintigraphy with 201Tl: II. Clinical Applications (Coronary Heart Disease)

Reproducibility of myocardial thallium‐201 washout in studies applying a standardized dipyridamole stress protocol

Longitudinal (Natural History) Studies of Silent Myocardial Ischemia

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