Quantitative ultrasound (QUS) on a specific region of interest (ROI) of the Os calcis: a new imaging technique

Jorgensen, Hildegard; Jørgensen, Lars Vincents; Hassager, Christian; Möllgaard, A; Christiansen, Claus

doi:10.1016/s0969-8043(97)00089-4

Cited by 2 publications

(1 citation statement)

References 6 publications

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“…Most devices are equipped with fixed ultrasound transducers and the coupling medium is either water or an ultrasonic gel. More recently, calcaneal two-dimensional ultrasound imaging devices have become available [10][11][12][13]. Because of the heterogeneity of the calcaneus, QUS measurements may be influenced by the location and size of the region of interest.…”

Section: Introductionmentioning

confidence: 99%

Measuring Skeletal Changes with Calcaneal Ultrasound Imaging in Healthy Children and Adults: The Influence of Size and Location of the Region of Interest

Bergh¹,

Noordam

Thijssen

et al. 2001

Osteoporosis International

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We measured the quantitative ultrasound (QUS) parameters broadband ultrasound attenuation (BUA) and speed of sound (SOS) at the calcaneus using an ultrasound imaging device (UBIS 3000) in 698 healthy Caucasian male and female subjects (110 prepubertal, 356 pubertal/adolescent and 210 adult) between 6 and 77 years of age. The influence of different region of interest (ROI) diameters (6-20 mm) and software techniques (automatic (ROIaut), copied (ROIcop) and fixed coordinate (ROIfix) measurements) on annual rate of change, trend assessment interval (TAI; an estimate of the follow-up time required for measuring a true change), percentage of positioning errors (positioning of the ROI partly at the cortical edge or even partly beyond the calcaneus) and short-term precision error was studied. When using ROI diameters increasing from 8 to 20 mm, the annual rate of change of BUA and SOS did not change in adults, but was higher in prepubertal subjects (when subjects with positioning errors were excluded) as well as in pubertal/adolescent subjects. TAIs for BUA were shortest when using ROIaut with ROI diameters between 8 and 14 mm (TAI between 1.2 and 1.5 years for prepubertal boys and pubertal/adolescent subjects, 2.4 years for prepubertal girls, 2.7 years for postmenopausal women, and 9 years in men and premenopausal women). TAIs for SOS were 4 years or more, except for postmenopausal women (2.1 years) and prepubertal boys (3.2 years). Measurements with large ROI diameters, especially with fixed region coordinates, resulted in a high percentage of positioning errors and mostly in longer TAIs. Analysis of the short-term precision errors did not reveal these important differences between the various ROI diameters. Our results indicate that calcaneal ultrasound imaging may be useful for measuring skeletal changes in healthy children, especially with BUA, and in postmenopausal women with BUA and SOS using an automatic measurement in the region of lowest attenuation. ROI diameters of 12 mm should be used in prepubertal subjects and of 14 mm in pubertal/adolescent and adult subjects.

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Section: Introductionmentioning

confidence: 99%

Measuring Skeletal Changes with Calcaneal Ultrasound Imaging in Healthy Children and Adults: The Influence of Size and Location of the Region of Interest

Bergh¹,

Noordam

Thijssen

et al. 2001

Osteoporosis International

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Broadband ultrasound attenuation in the calcaneal region: a comparative study of single-position versus scanning systems

Maia

Costa

Neto³

et al. 2008

IEEE Trans. Ultrason., Ferroelect., Freq. Contr.

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This work describes a system developed to measure the broadband ultrasound attenuation (BUA) in the calcaneal region. The patient's calcanei were inspected using a microcomputer-controlled X-Y axis displacement unit with two 500-kHz, central-frequency, ultrasound transducers. The transducers facing each other are submerged in a small water tank with a support for the patient's foot between them. The system allows data to be collected from a single position or by scanning the calcaneal region to obtain a BUA map. Tests were carried out on 201 patients (110 using the single-position method, and 91 using the scanning method). The results were compared with those of densitometry tests performed using the dual energy X-ray absorptiometry (DEXA) technique (single position: r=0.50; P<0.0001; scanner: r=0.75; P<0.0001). It was concluded that the single position method is more susceptible to errors due to the difficulty in positioning the transducers relative to the calcaneus. The scanning method provides better results and can be used to screen patients before referring them for DEXA.

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Quantitative ultrasound (QUS) on a specific region of interest (ROI) of the Os calcis: a new imaging technique

Cited by 2 publications

References 6 publications

Measuring Skeletal Changes with Calcaneal Ultrasound Imaging in Healthy Children and Adults: The Influence of Size and Location of the Region of Interest

Measuring Skeletal Changes with Calcaneal Ultrasound Imaging in Healthy Children and Adults: The Influence of Size and Location of the Region of Interest

Broadband ultrasound attenuation in the calcaneal region: a comparative study of single-position versus scanning systems

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