Multi-qubit quantum Rabi model, which is a fundamental model describing light-matter interaction, plays an important role in various physical systems. In this paper, we propose a theoretical method to simulate multi-qubit quantum Rabi model in a circuit quantum electrodynamics system. By means of external transversal and longitudinal driving fields, an effective Hamiltonian describing the multi-qubit quantum Rabi model is derived. The effective frequency of the resonator and the effective splitting of the qubits depend on the external driving fields. By adjusting the frequencies and the amplitudes of the driving fields, the stronger coupling regimes could be reached. The numerical simulation shows that our proposal works well in a wide range of parameter space. Moreover, our scheme can be utilized to generate two-qubit gate, Schrödinger states, and multi-qubit GHZ states. The maximum displacement of the Schrödinger cat states can be enhanced by increasing the number of the qubits and the relative coupling strength. It should be mention that we can obtain high fidelity Schrödinger cat states and multi-qubit GHZ states even the system suffering dissipation. The presented proposal may open a way to study the stronger coupling regimes whose coupling strength is far away from ultrastrong coupling regimes.