We realize a quantum-gas microscope for fermionic 40 K atoms trapped in an optical lattice, which allows one to probe strongly correlated fermions at the single-atom level. We combine 3D Raman sideband cooling with high-resolution optics to simultaneously cool and image individual atoms with single-latticesite resolution at a detection fidelity above 95%. The imaging process leaves the atoms predominantly in the 3D motional ground state of their respective lattice sites, inviting the implementation of a Maxwell's demon to assemble low-entropy many-body states. Single-site-resolved imaging of fermions enables the direct observation of magnetic order, time-resolved measurements of the spread of particle correlations, and the detection of many-fermion entanglement. DOI: 10.1103/PhysRevLett.114.193001 PACS numbers: 37.10.De, 03.75.Ss, 37.10.Jk, 67.85.Lm The collective behavior of fermionic particles governs the structure of the elements, the workings of hightemperature superconductors and colossal magnetoresistance materials, and the properties of nuclear matter. Yet our understanding of strongly interacting Fermi systems is limited, due in part to the antisymmetry requirement on the many-fermion wave function and the resulting "fermion sign problem" [1]. In recent years, ultracold atomic quantum gases have enabled quantitative experimental tests of theories of strongly interacting fermions [2][3][4][5]. In particular, fermions trapped in optical lattices can directly simulate the physics of electrons in a crystalline solid, shedding light on novel physical phenomena in materials with strong electron correlations. A major effort is devoted to the realization of the Fermi-Hubbard model at low entropies, believed to capture the essential aspects of high-T c superconductivity [6][7][8][9][10][11][12]. For bosonic atoms, a new set of experimental probes ideally suited for the observation of magnetic order and correlations has become available with the advent of quantum-gas microscopes [13][14][15], enabling high-resolution imaging of Hubbardtype lattice systems at the single-atom level. They allowed the direct observation of spatial structures and ordering in the Bose-Hubbard model [14,16] and of the intricate correlations and dynamics in these systems [17,18]. A longstanding goal has been to realize such a quantum-gas microscope for fermionic atoms. This would enable the direct probing and control at the single-lattice-site level of strongly correlated fermion systems, in particular the Fermi-Hubbard model, in regimes that cannot be described by current theories. These prospects have sparked significant experimental efforts to realize site-resolved, highfidelity imaging of ultracold fermions, but this goal has so far remained elusive.In the present work, we realize a quantum-gas microscope for fermionic 40 K atoms by combining 3D Raman sideband cooling with a high-resolution imaging system. The imaging setup incorporates a hemispherical solid immersion lens optically contacted to the vacuum window [ Fig. 1(a)]. In ...