Quantum dot-based FRET nanosensors for Talin-membrane assembly and mechanosensing
Audrey Ntadambanya,
Julien Pernier,
Violaine David
et al.
Abstract:Understanding the mechanisms of assembly and disassembly of macromolecular structures in cells relies on solving biomolecular interactions. However, those interactions often remain unclear because tools to track molecular dynamics are not sufficiently resolved in time or space. In this study, we present a straightforward method for resolving inter- and intra- molecular interactions in cell adhesive machinery, using quantum dot (QD) based Förster resonance energy transfer (FRET) nanosensors. Using mechanosensit… Show more
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