Quantum Dots: An Emerging Approach for Cancer Therapy

Abstract

Nanotechnology is indisputably a scientific technique that offers the prospect of new therapies, and hope, for the treatment of malignant illnesses. It is a novel technology that offers new approaches for the diagnosis and management of diverse diseases. Although the discovery of Quantum dots (QD) nano-transporters has already led to a few positive developments, QD nano-transporters are still at their initial stage, though have yet proven valuable to society. The excertion of QD indicates conversion in natural imaging along with photograph have established incredible suitability in bio-imaging, new drug development, targeted gene deliverance, biosensing, photodynamic treatment as well as diagnosis. The present review aimed to confer the significance of QD in diagnosis as well as in management of cancer. This review aims to impart fundamental insight as well as conception of QD its merits, properties, utilization as well as mode of action. This review highlight of different designing schemes of QD like hydrothermal, drop-casting, ultrasonic, solvothermal, spin-coating, atomic layer desorption, layer by layer, polymethylmethacrylate aided-transfer, electrochemical, ion beam sputtering deposition. Moreover, we have elaborated on the diverse researches related to cytotoxic examination to reveal that QDs are harmless. Concisely, the present review summarizes the fabrication schemes, current research and utilization of QD in cancer treatment.

Carbon Dots: Opportunities and Challenges in Cancer Therapy

“…CDs have been used as contrast agents for in vivo optical imaging because of their new photo physical features [ 20 , 66 ]. The most used method for optical imaging is direct PL imaging using light irradiation.…”

“…When compared to conventional chemotherapy and radiotherapy, the selectivity provided by PDT and PTT can dramatically lower systemic toxicity. As a result, CDs with inherent photo-theranostic capabilities have demonstrated significant promise for use in the treatment of tumors [ 20 , 21 ]. The main objective of the present review is to highlight synthesis techniques of CDs and the prospects of CDs as nanotheranostic agents for anticancer applications.…”

Dual targeting multiwalled carbon nanotubes for improved neratinib delivery in breast cancer

“…The application of nanotechnology to carbon-based materials has led to the development of a variety of nanostructures, including carbon-based nanoribbons, quantum dots, nanowires, … etc. 46–48 Among them, CNTs have been emerged as a promising nano-delivery vehicle that have significant several advantages over conventional drug delivery technologies in the realm of biological applications. The huge internal cavities of these nanotubes can afford efficient drug loading of many therapeutic entities such as anticancer drugs.…”

“…etc. [46][47][48] Among them, CNTs have been emerged as a promising nano-delivery vehicle that have signicant several advantages over conventional drug delivery technologies in the realm of biological applications. The huge internal cavities of these nanotubes can afford efficient drug loading of many therapeutic entities such as anticancer drugs.…”

Nanoparticle-Labeled Exosomes as Theranostic Agents: A Review

“…However, the clinical applications of these NPs have limitations . For example, when it comes to using NPs for a targeted photothermal therapy, most of the NPs such as QDs and IONPs require a high temperature of ∼50 °C that causes damage to the surrounding healthy tissue. , In addition, several researchers have confirmed the cytotoxicity of QDs . Moreover, drug conjugated AuNPs have a faster drug release .…”